Detalhe da pesquisa
1.
PR-619, a General Inhibitor of Deubiquitylating Enzymes, Diminishes Cisplatin Resistance in Urothelial Carcinoma Cells through the Suppression of c-Myc: An In Vitro and In Vivo Study.
Int J Mol Sci
; 22(21)2021 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769137
2.
dBRWD3 Regulates Tissue Overgrowth and Ectopic Gene Expression Caused by Polycomb Group Mutations.
PLoS Genet
; 12(9): e1006262, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27588417
3.
Trifluoperazine, an Antipsychotic Drug, Effectively Reduces Drug Resistance in Cisplatin-Resistant Urothelial Carcinoma Cells via Suppressing Bcl-xL: An In Vitro and In Vivo Study.
Int J Mol Sci
; 20(13)2019 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31262032
4.
Histone Deacetylase Inhibitor, Trichostatin A, Synergistically Enhances Paclitaxel-Induced Cytotoxicity in Urothelial Carcinoma Cells by Suppressing the ERK Pathway.
Int J Mol Sci
; 20(5)2019 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30866433
5.
MLN4924, a Protein Neddylation Inhibitor, Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis.
Int J Mol Sci
; 20(1)2018 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30586948
6.
Anti-tumor effects of deubiquitinating enzyme inhibitor PR-619 in human chondrosarcoma through reduced cell proliferation and endoplasmic reticulum stress-related apoptosis.
Am J Cancer Res
; 13(7): 3055-3066, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37559983
7.
Epstein-Barr virus DNase (BGLF5) induces genomic instability in human epithelial cells.
Nucleic Acids Res
; 38(6): 1932-49, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20034954
8.
The UCHL5 inhibitor b-AP15 overcomes cisplatin resistance via suppression of cancer stemness in urothelial carcinoma.
Mol Ther Oncolytics
; 26: 387-398, 2022 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36090476
9.
CDK7 inhibition by THZ1 suppresses cancer stemness in both chemonaïve and chemoresistant urothelial carcinoma via the hedgehog signaling pathway.
Cancer Lett
; 507: 70-79, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33741425
10.
THZ1, a covalent CDK7 inhibitor, enhances gemcitabine-induced cytotoxicity via suppression of Bcl-2 in urothelial carcinoma.
Am J Cancer Res
; 11(1): 171-180, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33520367
11.
Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response.
Blood
; 112(9): 3661-70, 2008 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18711002
12.
The covalent CDK7 inhibitor THZ1 enhances temsirolimus-induced cytotoxicity via autophagy suppression in human renal cell carcinoma.
Cancer Lett
; 471: 27-37, 2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31812697
13.
Neddylation inhibitor, MLN4924 suppresses angiogenesis in huvecs and solid cancers: in vitro and in vivo study.
Am J Cancer Res
; 10(3): 953-964, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32266102
14.
Suppression of Angiogenesis by Targeting Cyclin-Dependent Kinase 7 in Human Umbilical Vein Endothelial Cells and Renal Cell Carcinoma: An In Vitro and In Vivo Study.
Cells
; 8(11)2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31752390
15.
The Deubiquitinating Enzyme Inhibitor PR-619 Enhances the Cytotoxicity of Cisplatin via the Suppression of Anti-Apoptotic Bcl-2 Protein: In Vitro and In Vivo Study.
Cells
; 8(10)2019 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31627336
16.
Correction to: Trichostatin A, a histone deacetylase inhibitor, induces synergistic cytotoxicity with chemotherapy via suppression of Raf/MEK/ERK pathway in urothelial carcinoma.
J Mol Med (Berl)
; 97(3): 435-436, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30741319
17.
Trichostatin A, a histone deacetylase inhibitor, induces synergistic cytotoxicity with chemotherapy via suppression of Raf/MEK/ERK pathway in urothelial carcinoma.
J Mol Med (Berl)
; 96(12): 1307-1318, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30288546
18.
Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activity.
Sci Rep
; 7(1): 3180, 2017 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28600541
19.
Epigallocatechin Gallate Attenuates Partial Bladder Outlet Obstruction-induced Bladder Injury via Suppression of Endoplasmic Reticulum Stress-related Apoptosis-In Vivo Study.
Urology
; 91: 242.e1-9, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26820120
20.
MLN4924 Synergistically Enhances Cisplatin-induced Cytotoxicity via JNK and Bcl-xL Pathways in Human Urothelial Carcinoma.
Sci Rep
; 5: 16948, 2015 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26592553