Detalhe da pesquisa
1.
In Silico Prediction of N-Nitrosamine Formation Pathways of Pharmaceutical Products.
Chem Pharm Bull (Tokyo)
; 72(2): 166-172, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38296559
2.
Origin of the kinetic HDAC2-selectivity of an HDAC inhibitor.
J Comput Chem
; 44(18): 1604-1609, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37074817
3.
In silico optimization of peptides that inhibit Wnt/ß-catenin signaling.
Bioorg Med Chem
; 84: 117264, 2023 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37003158
4.
CRBN ligand expansion for hematopoietic prostaglandin D2 synthase (H-PGDS) targeting PROTAC design and their in vitro ADME profiles.
Bioorg Med Chem
; 84: 117259, 2023 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37018877
5.
Development of versatile solid-phase methods for syntheses of PROTACs with diverse E3 ligands.
Bioorg Med Chem
; 86: 117293, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37126968
6.
Development of a penetratin-conjugated stapled peptide that inhibits Wnt/ß-catenin signaling.
Bioorg Med Chem
; 73: 117021, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36198218
7.
Identification of Novel Histone Deacetylase 6-Selective Inhibitors Bearing 3,3,3-Trifluorolactic Amide (TFLAM) Motif as a Zinc Binding Group.
Chembiochem
; 22(22): 3158-3163, 2021 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34224197
8.
Synthesis of Norgestomet and its 17ß-isomer and evaluation of their agonistic activities against progesterone receptor.
Bioorg Med Chem
; 49: 116425, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34607200
9.
Discovery of novel tetrahydrobenzo[b]thiophene-3-carbonitriles as histone deacetylase inhibitors.
Bioorg Chem
; 110: 104801, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33756235
10.
Peptide Stapling Improves the Sustainability of a Peptide-Based Chimeric Molecule That Induces Targeted Protein Degradation.
Int J Mol Sci
; 22(16)2021 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445478
11.
Identification of ortho-hydroxy anilide as a novel scaffold for lysine demethylase 5 inhibitors.
Bioorg Med Chem Lett
; 29(10): 1173-1176, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30928196
12.
Synthesis of ß-allylbutenolides via one-pot copper-catalyzed hydroallylation/cyclization of γ-hydroxybutynoate derivatives.
J Org Chem
; 79(10): 4503-11, 2014 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24745963
13.
Structural analysis of an lysergic acid diethylamide (LSD) analogue N-methyl-N-isopropyllysergamide (MiPLA): Insights from Rotamers in NMR spectra.
Drug Test Anal
; 2023 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37830386
14.
Structure-activity relationship study of PROTACs against hematopoietic prostaglandin D2 synthase.
RSC Med Chem
; 13(12): 1495-1503, 2022 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36561070
15.
Development of Rapid and Facile Solid-Phase Synthesis of PROTACs via a Variety of Binding Styles.
ChemistryOpen
; 11(7): e202200131, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35822913
16.
Oligoarginine-Conjugated Peptide Foldamers Inhibiting Vitamin D Receptor-Mediated Transcription.
ACS Omega
; 7(50): 46573-46582, 2022 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36570290
17.
Cancer-Cell-Selective Targeting by Arylcyclopropylamine-Vorinostat Conjugates.
ACS Med Chem Lett
; 13(10): 1568-1573, 2022 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36262394
18.
Design, Synthesis, and Biological Evaluation of Lysine Demethylase 5â C Degraders.
ChemMedChem
; 16(10): 1609-1618, 2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33470543
19.
N+-C-H···O Hydrogen bonds in protein-ligand complexes.
Sci Rep
; 9(1): 767, 2019 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30683882
20.
Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the "Selectivity Pocket", Substrate-Binding Site, and NAD+-Binding Site.
J Med Chem
; 62(12): 5844-5862, 2019 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31144814