Detalhe da pesquisa
1.
HIV-1 Integrase Binds the Viral RNA Genome and Is Essential during Virion Morphogenesis.
Cell
; 166(5): 1257-1268.e12, 2016 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27565348
2.
Virus specificity and nucleoporin requirements for MX2 activity are affected by GTPase function and capsid-CypA interactions.
PLoS Pathog
; 20(3): e1011830, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38512975
3.
HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA.
J Virol
; 96(18): e0101122, 2022 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36094316
4.
A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site.
PLoS Pathog
; 17(7): e1009671, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34293041
5.
LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes.
Genes Dev
; 29(21): 2287-97, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26545813
6.
The Pleiotropic Effects of YBX1 on HTLV-1 Transcription.
Int J Mol Sci
; 24(17)2023 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37685922
7.
ATR prevents Ca2+ overload-induced necrotic cell death through phosphorylation-mediated inactivation of PARP1 without DNA damage signaling.
FASEB J
; 35(5): e21373, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33811702
8.
HIV-1 integrase binding to genomic RNA 5'-UTR induces local structural changes in vitro and in virio.
Retrovirology
; 18(1): 37, 2021 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34809662
9.
Exploring the Free-Energy Landscape and Thermodynamics of Protein-Protein Association.
Biophys J
; 119(6): 1226-1238, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32877664
10.
N6-Methyladenosine-binding proteins suppress HIV-1 infectivity and viral production.
J Biol Chem
; 293(34): 12992-13005, 2018 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29976753
11.
Structure of the Brd4 ET domain bound to a C-terminal motif from γ-retroviral integrases reveals a conserved mechanism of interaction.
Proc Natl Acad Sci U S A
; 113(8): 2086-91, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26858406
12.
Resistance to pyridine-based inhibitor KF116 reveals an unexpected role of integrase in HIV-1 Gag-Pol polyprotein proteolytic processing.
J Biol Chem
; 292(48): 19814-19825, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972144
13.
The FACT Complex Promotes Avian Leukosis Virus DNA Integration.
J Virol
; 91(7)2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28122976
14.
Allosteric HIV-1 Integrase Inhibitors Lead to Premature Degradation of the Viral RNA Genome and Integrase in Target Cells.
J Virol
; 91(17)2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28615207
15.
Use of chemical modification and mass spectrometry to identify substrate-contacting sites in proteinaceous RNase P, a tRNA processing enzyme.
Nucleic Acids Res
; 44(11): 5344-55, 2016 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27166372
16.
HIV-1 Integrase-Targeted Short Peptides Derived from a Viral Protein R Sequence.
Molecules
; 23(8)2018 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30049955
17.
A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain.
J Biol Chem
; 291(45): 23569-23577, 2016 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27645997
18.
Development of Potent Antiviral Drugs Inspired by Viral Hexameric DNA-Packaging Motors with Revolving Mechanism.
J Virol
; 90(18): 8036-46, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27356896
19.
Akt Pathway Activation by Human T-cell Leukemia Virus Type 1 Tax Oncoprotein.
J Biol Chem
; 290(43): 26270-81, 2015 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26324707
20.
A new class of multimerization selective inhibitors of HIV-1 integrase.
PLoS Pathog
; 10(5): e1004171, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24874515