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1.
Phys Rev Lett ; 129(12): 120502, 2022 Sep 16.
Artigo em Inglês | MEDLINE | ID: mdl-36179159

RESUMO

Superradiance, characterized by the collective, coherent emission of light from an excited ensemble of emitters, generates photonic signals on timescales faster than the natural lifetime of an individual atom. The rapid exchange of coherence between atomic emitters and photonic fields in the superradiant regime enables a fast, broadband quantum memory. We demonstrate this superradiance memory mechanism in an ensemble of cold rubidium atoms and verify that this protocol is suitable for pulses on timescales shorter than the atoms' natural lifetime. Our simulations show that the superradiance memory protocol yields the highest bandwidth storage among protocols in the same system. These high-bandwidth quantum memories provide unique opportunities for fast processing of optical and microwave photonic signals, with applications in large-scale quantum communication and quantum computing technologies.

2.
Nature ; 546(7659): 481-482, 2017 06 21.
Artigo em Inglês | MEDLINE | ID: mdl-28640266
3.
J Clin Microbiol ; 54(9): 2251-61, 2016 09.
Artigo em Inglês | MEDLINE | ID: mdl-27335149

RESUMO

Rapid diagnosis and treatment of infectious meningitis and encephalitis are critical to minimize morbidity and mortality. Comprehensive testing of cerebrospinal fluid (CSF) often includes Gram stain, culture, antigen detection, and molecular methods, paired with chemical and cellular analyses. These methods may lack sensitivity or specificity, can take several days, and require significant volume for complete analysis. The FilmArray Meningitis/Encephalitis (ME) Panel is a multiplexed in vitro diagnostic test for the simultaneous, rapid (∼1-h) detection of 14 pathogens directly from CSF specimens: Escherichia coli K1, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis, Streptococcus pneumoniae, Streptococcus agalactiae, cytomegalovirus, enterovirus, herpes simplex virus 1 and 2, human herpesvirus 6, human parechovirus, varicella-zoster virus, and Cryptococcus neoformans/Cryptococcus gattii We describe a multicenter evaluation of 1,560 prospectively collected CSF specimens with performance compared to culture (bacterial analytes) and PCR (all other analytes). The FilmArray ME Panel demonstrated a sensitivity or positive percentage of agreement of 100% for 9 of 14 analytes. Enterovirus and human herpesvirus type 6 had agreements of 95.7% and 85.7%, and L. monocytogenes and N. meningitidis were not observed in the study. For S. agalactiae, there was a single false-positive and false-negative result each, for a sensitivity and specificity of 0 and 99.9%, respectively. The specificity or negative percentage of agreement was 99.2% or greater for all other analytes. The FilmArray ME Panel is a sensitive and specific test to aid in diagnosis of ME. With use of this comprehensive and rapid test, improved patient outcomes and antimicrobial stewardship are anticipated.


Assuntos
Líquido Cefalorraquidiano/microbiologia , Líquido Cefalorraquidiano/virologia , Encefalite/diagnóstico , Meningite/diagnóstico , Técnicas de Diagnóstico Molecular/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Bactérias/classificação , Bactérias/isolamento & purificação , Infecções Bacterianas/diagnóstico , Infecções Bacterianas/microbiologia , Infecções Fúngicas do Sistema Nervoso Central/diagnóstico , Infecções Fúngicas do Sistema Nervoso Central/microbiologia , Criança , Pré-Escolar , Encefalite/etiologia , Feminino , Fungos/classificação , Fungos/isolamento & purificação , Humanos , Lactente , Recém-Nascido , Masculino , Meningite/etiologia , Pessoa de Meia-Idade , Estudos Prospectivos , Sensibilidade e Especificidade , Fatores de Tempo , Viroses/diagnóstico , Viroses/virologia , Vírus/classificação , Vírus/isolamento & purificação , Adulto Jovem
4.
Nature ; 520(7545): 36-7, 2015 Apr 02.
Artigo em Inglês | MEDLINE | ID: mdl-25832398
5.
Nature ; 505(7485): 627-8, 2014 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-24476885
6.
Proc Natl Acad Sci U S A ; 109(27): 10811-4, 2012 Jul 03.
Artigo em Inglês | MEDLINE | ID: mdl-22699494

RESUMO

Measurement techniques based upon the Hall effect are invaluable tools in condensed-matter physics. When an electric current flows perpendicular to a magnetic field, a Hall voltage develops in the direction transverse to both the current and the field. In semiconductors, this behavior is routinely used to measure the density and charge of the current carriers (electrons in conduction bands or holes in valence bands)--internal properties of the system that are not accessible from measurements of the conventional resistance. For strongly interacting electron systems, whose behavior can be very different from the free electron gas, the Hall effect's sensitivity to internal properties makes it a powerful tool; indeed, the quantum Hall effects are named after the tool by which they are most distinctly measured instead of the physics from which the phenomena originate. Here we report the first observation of a Hall effect in an ultracold gas of neutral atoms, revealed by measuring a Bose-Einstein condensate's transport properties perpendicular to a synthetic magnetic field. Our observations in this vortex-free superfluid are in good agreement with hydrodynamic predictions, demonstrating that the system's global irrotationality influences this superfluid Hall signal.


Assuntos
Temperatura Baixa , Magnetismo/métodos , Teoria Quântica , Semicondutores , Condutividade Elétrica , Elétrons , Estudos de Avaliação como Assunto , Hidrodinâmica
7.
Science ; 377(6606): 576-577, 2022 08 05.
Artigo em Inglês | MEDLINE | ID: mdl-35926056

RESUMO

Ordered patterns reoccur over time in an ultracold atomic gas trapped in light.

9.
J Mol Diagn ; 22(8): 1063-1069, 2020 08.
Artigo em Inglês | MEDLINE | ID: mdl-32454221

RESUMO

Nasal colonization with Staphylococcus aureus is a well-referenced risk factor for postoperative surgical site infections (SSIs). Our health care system that performs >40,000 surgeries per year assessed both the diagnostic accuracy of the BD MAX StaphSR assay (MAX StaphSR), a PCR-based test that detects and differentiates S. aureus and methicillin-resistant S. aureus (MRSA), compared with our standard of care culture and the subsequent clinical impact on SSIs 1 year after implementation. In addition, residual specimens were tested by broth-enriched culture. Performance parameters for all methods were determined using latent class analysis. Direct culture was the least sensitive for S. aureus (85.1%) and MRSA (76.7%), whereas the MAX StaphSR assay and broth-enriched culture had similar sensitivities (96.7%) for MRSA. Prospective assessment using MAX StaphSR during a 1-year, postimplementation period revealed a lower rate of SSIs per 100 targeted surgeries (0.3) compared with MRSA-only screening (1.10) and no screening (2.28) (P < 0.05 for StaphSR versus MRSA-only screening and StaphSR versus no testing). MRSA and methicillin-sensitive S. aureus SSIs occurred equally (n = 14 each). The MAX StaphSR assay provided accurate detection of both S. aureus and MRSA nasal colonization in presurgical patients, allowing infection prevention measures, including presurgical prophylaxis, to be implemented in a timely and consistent manner to avoid SSIs.


Assuntos
Técnicas de Cultura/métodos , Confiabilidade dos Dados , Testes Diagnósticos de Rotina/métodos , Staphylococcus aureus Resistente à Meticilina/genética , Staphylococcus aureus Resistente à Meticilina/isolamento & purificação , Reação em Cadeia da Polimerase/métodos , Período Pré-Operatório , Infecções Estafilocócicas/diagnóstico , Infecção da Ferida Cirúrgica/diagnóstico , Seguimentos , Humanos , Técnicas de Diagnóstico Molecular/métodos , Estudos Prospectivos , Sensibilidade e Especificidade , Infecções Estafilocócicas/microbiologia , Infecção da Ferida Cirúrgica/microbiologia
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