The Effect of Oral Care with Black Mulberry Syrup on Oral Mucositis in Patients With COPD: A Mixed Study.

Background: Oral mucositis often affects the quality of life of patients living with Chronic Obstructive Pulmonary Disease (COPD). Its symptoms include loss of oral mucous membranes, ulceration, bleeding and pain as well as bacterial, fungal and viral infections of the oral mucosa. Objectives: This study was carried out to investigate the effect of oral care with black mulberry syrup on oral mucositis healing in patients with COPD. Design: This mixed study was carried out in two stages- quantitative and qualitative. The quantitative stage was conducted as a randomized controlled experimental study while the qualitative stage was conducted by in-depth interview method. Setting: This study was conducted at the chest diseases clinic of a tertiary hospital in Turkey. Participants: The randomized controlled experimental study was completed with a total of 40 patients who had been diagnosed with COPD and oral mucositis between March 2017 and June 2018. They were divided into intervention and control groups consisting of 20 patients each. The qualitative study was conducted on 10 patients in the intervention group. Intervention: Patients in the intervention group gargled with 5 ml of black mulberry syrup for an average of 1 minute and swallowed it upon completion. They did this 3 times a day after meals for a period of 15 days after which they were interviewed. Outcome Measures: The quantitative data was collected using the Patient Information Form, Oral Evaluation Guideline, and WHO Oral Mucositis Scoring Index, while the qualitative data was collected using the in-depth interview form. Patients' oral mucosa was assessed a total of 3 times during 3 interviews held on the first, seventh and fifteenth days of the study. Results: There was a significant decrease in scores of oral mucositis of the patients in the intervention group at the second and third follow-ups. Oral mucositis of the intervention and the control groups healed at an average of 9.1 ± 2.5 days and 12.1 ± 1.4 days, respectively. In addition, oral care with black mulberry syrup was found to alleviate mucositis-related symptoms. Conclusion: Oral care with black mulberry syrup accelerates mucositis healing and alleviates mucositis-related symptoms.

Is there any Relationship between Acne Vulgaris and Diet Inflammatory Index in Women? / ¿Existe alguna relación entre el acné vulgar y el índice inflamatorio de la dieta en mujeres?

Background: Acne vulgaris (AV) is a chronic inflammatorydisease that can be seen at any stage of life. Diet is thoughtto be effective in AV formation. The dietary inflammatory in-dex (DII) determines how inflammatory a diet is. We hypoth-esized that DII is associated with AV and a biochemical pa-rameter in women. Methods: In the study performed on 68 women (34 casesand 34 controls) between the ages of 19-35 at Erciyes University Faculty of Medicine Dermatology Polyclinic, AVseverity was determined by the responsible dermatologist andblood samples were taken from the individuals. Three-dayfood consumption records from women were used in the DIIcalculation. DII scores were divided into tertiles according towomen with and without AV. The socio-demographic information and anthropometric measurements of the women wererecorded face-to-face with a questionnaire. Results: Cases had higher DII scores than controls. WhenDII scores were divided into tertiles, the most proinflammatory group was found to be tertile 3+. It was determined thatthe women in the most proinflammatory group had higherbody weight and body mass index (BMI) values compared toother tertiles. Conclusion: The study’s results suggest that as the DIIscore increases, the diet has a pro-inflammatory effect associated with AV. Including sufficient anti-inflammatory foods in their diets to decrease DII of individuals will help prevent AVformation and/or reduce lesions.(AU)

Introducción: El acné vulgaris (AV) es una enfermedad inflamatoria crónica que puede aparecer en cualquier etapa de la vida. Se cree que la dieta es efectiva en la formación del AV. El índice inflamatorio dietético (DII) determina cuán inflamatoria es una dieta. Hipotetizamos que el DII está asociado con AV y un parámetro bioquímico en mujeres. Métodos: El estudio incluyó a 34 mujeres con casos y 34 mujeres sanas como control que acudieron a un hospital. Un dermatólogo responsable determinó la gravedad del AV y se recopilaron muestras de sangre de las personas. El DII se calculó utilizando registros de consumo de alimentos de tres días de mujeres. El DII se ajustó según los terciles en mujeres con y sin AV. El investigador responsable utilizó el enfoque de entrevista cara a cara para registrar la información sociodemográfica y las medidas antropométricas de las mujeres. Resultados: Los casos tenían puntuaciones DII más altas que los controles. Cuando se dividieron en terciles, el grupo con la puntuación DII más alta y el grupo más proinflamatorio fueron las mujeres en el grupo tercil 3+ (4,93 ± 1,37). Se encontró que aquellos en el grupo más proinflamatorio tenían más sobrepeso (58,27 ± 6,63 kg), y el índice de masa corporal (IMC) (21,94 ± 2,80 kg/m2) era mayor. Conclusión: Los resultados del estudio sugieren que a medida que aumenta la puntuación DII, la dieta tiene un efecto proinflamatorio asociado con el AV. Incluir suficientes alimentos antiinflamatorios en su dieta para disminuir el DII de las personas ayudará a prevenir la formación de AV y/o reducir las lesiones.(AU)