Detalhe da pesquisa
1.
Tumour, whole-blood, plasma and tissue concentrations of metformin in lung cancer patients.
Br J Clin Pharmacol
; 89(3): 1027-1035, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36164710
2.
Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple Transgenic Alzheimer's Disease Mice.
Int J Mol Sci
; 24(13)2023 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446191
3.
The effect of sonidegib (LDE225) on the pharmacokinetics of bupropion and warfarin in patients with advanced solid tumours.
Br J Clin Pharmacol
; 87(3): 1291-1302, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32736411
4.
An Inhibitor of Fatty Acid Synthase Thioesterase Domain with Improved Cytotoxicity against Breast Cancer Cells and Stability in Plasma.
J Pharmacol Exp Ther
; 371(1): 171-185, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31300609
5.
Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma.
J Neurooncol
; 144(3): 563-572, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31399936
6.
Phase 1 trial of rituximab, lenalidomide, and ibrutinib in previously untreated follicular lymphoma: Alliance A051103.
Blood
; 128(21): 2510-2516, 2016 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27697771
7.
Immune modulation associated with vascular endothelial growth factor (VEGF) blockade in patients with glioblastoma.
Cancer Immunol Immunother
; 66(3): 379-389, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27942839
8.
Spotlight commentary: Navigating between financial risks and improved treatment outcomes with immune checkpoint inhibitors in cancer patients: The need for biomarker identification and dose optimization.
Br J Clin Pharmacol
; 88(12): 5060-5063, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36206769
9.
Effect of ketoconazole, a strong CYP3A inhibitor, on the pharmacokinetics of venetoclax, a BCL-2 inhibitor, in patients with non-Hodgkin lymphoma.
Br J Clin Pharmacol
; 83(4): 846-854, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27859472
10.
Challenges faced when identifying patients for combination immunotherapy.
Future Oncol
; 13(18): 1607-1618, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28835114
11.
Medicamenta ad sentinam, et defectum vitae: Drugs and failure of the pump of life-cardiotoxicity of oncotherapeutics.
Br J Clin Pharmacol
; 87(3): 735-737, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33073394
12.
S-Warfarin Limited Sampling Models to Estimate Area Under the Concentration Versus Time Curve for Cytochrome P450 2C9 Baseline Activity and After Induction.
Ther Drug Monit
; 38(3): 383-7, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26818625
13.
Taking the brake off the immune system: Hypotheses, trials, tribulations, and the evolving discipline of clinical immunopharmacology.
Br J Clin Pharmacol
; 86(9): 1674-1677, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32770557
14.
Vincristine activates c-Jun N-terminal kinase in chronic lymphocytic leukaemia in vivo.
Br J Clin Pharmacol
; 80(3): 493-501, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25753324
15.
Pharmacodynamics and pharmacokinetics of oral topotecan in patients with advanced solid tumours and impaired renal function.
Br J Clin Pharmacol
; 80(2): 253-66, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25677219
16.
Vatalanib population pharmacokinetics in patients with myelodysplastic syndrome: CALGB 10105 (Alliance).
Br J Clin Pharmacol
; 78(5): 1005-13, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24838014
17.
The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance).
Pharmacogenet Genomics
; 23(1): 29-33, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23188068
18.
A proof of principle clinical trial to determine whether conjugated linoleic acid modulates the lipogenic pathway in human breast cancer tissue.
Breast Cancer Res Treat
; 138(1): 175-83, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23417336
19.
A phase 1b study of humanized KS-interleukin-2 (huKS-IL2) immunocytokine with cyclophosphamide in patients with EpCAM-positive advanced solid tumors.
BMC Cancer
; 13: 20, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23320927
20.
Manipulating the apoptotic pathway: potential therapeutics for cancer patients.
Br J Clin Pharmacol
; 76(3): 381-95, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23782006