RESUMO
Achieving electrostatic control of quantum phases is at the frontier of condensed matter research. Recent investigations have revealed superconductivity tunable by electrostatic doping in twisted graphene heterostructures and in two-dimensional semimetals such as WTe2 (refs. 1-5). Some of these systems have a polar crystal structure that gives rise to ferroelectricity, in which the interlayer polarization exhibits bistability driven by external electric fields6-8. Here we show that bilayer Td-MoTe2 simultaneously exhibits ferroelectric switching and superconductivity. Notably, a field-driven, first-order superconductor-to-normal transition is observed at its ferroelectric transition. Bilayer Td-MoTe2 also has a maximum in its superconducting transition temperature (Tc) as a function of carrier density and temperature, allowing independent control of the superconducting state as a function of both doping and polarization. We find that the maximum Tc is concomitant with compensated electron and hole carrier densities and vanishes when one of the Fermi pockets disappears with doping. We argue that this unusual polarization-sensitive two-dimensional superconductor is driven by an interband pairing interaction associated with nearly nested electron and hole Fermi pockets.
RESUMO
The diversity seen in the mode of pharmacology and the numerous glutamate receptor subtypes have previously complicated drug development efforts. Nonetheless, recent clinical trials of drug candidates that accommodate the glutamatergic intricate pharmacology have yielded encouraging results. Target engagement is an important requirement for the advancement of central nervous system drug candidates into clinical trial. Positron emission tomography (PET) tracer technology has the unique ability to give the direct insight into the relationship between the level of receptor occupancy and the administered dose, thus establishing a direct link between the level of target exposure and the drug efficacy in human. This review is focused on the advancement of mGlu5 , mGlu 1 , and mGlu 2 receptor-related PET tracer technology: PET tracer development strategies, PET tracer selection in receptor occupancy studies, the scopes and limitations to use PET to measure receptor occupancy for the drug candidates with different pharmacology, and how to use the measurements of receptor occupancy as a translational biomarker for decision-making in an innovative drug development program.
Assuntos
Desenvolvimento de Medicamentos , Tomografia por Emissão de Pósitrons/métodos , Receptores de Glutamato Metabotrópico/metabolismo , Animais , HumanosRESUMO
A new monobasic leafhopper subgenus, Varicopsella (Multispinulosa) Li, Dai, and Li, subgen. nov., of the subfamily Macropsinae (Hemiptera: Auchenorrhyncha: Membracoidea: Cicadellidae) is proposed to accommodate Varicopsella (Multispinulosa) hamiltoni Li, Dai, and Li, sp. nov.from Guangxi province of China. The new subgenus and new species are described and illustrated. They can be distinguished mainly by characteristics of the fore wings with two anteapical cells; weak dorsoventrally flattened body; aedeagal shaft with paired apical processes on ventral margin; and the shape of the dorsal connective. An updated checklist and an illustrated key for identification of the species of Varicopsella along with geographical distributions of the species are given.
Assuntos
Hemípteros/anatomia & histologia , Hemípteros/classificação , Animais , Lista de Checagem , ChinaRESUMO
The genus Soractellus Evans, 1966 is reported for the first time based on a new species, Soractellus jianfengensis sp. nov., here described and illustrated from China. A key is given to distinguish all species of the genus. The type specimens of the new species are deposited in the Institute of Entomology, Guizhou University, Guiyang, China (GUGC).
Assuntos
Hemípteros/classificação , Distribuição Animal , Animais , China , Ecossistema , Genitália Masculina/anatomia & histologia , Hemípteros/anatomia & histologia , MasculinoRESUMO
Five new leafhopper species, Qadria bannaensis, Q. daliensis, Q. dongfanga, Q. guiyanga and Q. cucullata spp. nov. from Yunnan, Hainan and Guizhou Prov. of China are described and illustrated, and a key to all species of the genus Qadria is provided.
Assuntos
Hemípteros/anatomia & histologia , Hemípteros/classificação , Animais , China , Demografia , Feminino , Hemípteros/fisiologia , Masculino , Especificidade da EspécieRESUMO
The paper deals with a new leafhopper genus of Evacanthinae, Shortcrowna gen. nov., and four species of the genus, including three new combinations and one new species, Shortcrowna biguttata (Li & Wang, 2002) comb. nov., Shortcrowna flavocapitata (Kato, 1933) comb. nov., Shortcrowna nigrimargina (Li & Wang, 2002) comb. nov., Shortcrowna leishanensis sp. nov.. The differences between the new genus and the closely related genus Bundera Distant are discussed. A key to distinguish all species of the genus is given, and illustrations of genitalia are provided. The type specimens of new species are deposited in the Institute of Entomology, Guizhou University (GUGC).
Assuntos
Hemípteros/classificação , Animais , China , Feminino , Hemípteros/anatomia & histologia , MasculinoRESUMO
The species of the Oriental leafhopper genus Multiformis Li & Li are reviewed. A new species, Multiformis ramosus sp. nov., from Yunnan Province, China is described and a key to all known species of Multiformis is provided.
Assuntos
Hemípteros/anatomia & histologia , Hemípteros/classificação , Animais , China , Demografia , Hemípteros/fisiologia , Especificidade da EspécieRESUMO
The (nine) valid species of Japanagallia Ishihara, 1955 from Guizhou, and Yunnan Provinces, and Guangxi Autonomous Region of Southwest China are reviewed and four new species J. gracilenta sp. nov., J. neohamata sp. nov., J. trifurcata sp. nov. and J. viraktamathi sp. nov. are described and illustrated. These species can be distinguished by unique features of the aedeagus. J. hamata Zhang & Li, 1999 is redescribed and illustrated based on the holotype and material from Guizhou Province and Guangxi Autonomous Region. A checklist and a key for identification of species of the genus Japanagallia are provided along with a map showing the distribution of Japanagallia in Guizhou, and Yunnan Provinces, and Guangxi Autonomous Region.
Assuntos
Hemípteros/classificação , Animais , China , Geografia , Hemípteros/anatomia & histologia , MasculinoRESUMO
The group of Chinese Macropsis species dwelling on oak (Quercus spp.) is reviewed and nine species are recognized. Among them, three new species, Macropsis huangbana sp. nov. from Shaanxi and Yunnan Provinces, M. latiprocessa sp. nov. from Guizhou Province and M. longiprocessa sp. nov. from Yunnan Province, are described and illustrated; M. irenae Viraktamath, 1981 (= M. irrorata Tishechkin, 2002, nec Matsumura, 1912) is recorded from China and Japan for the first time; M. meifengensis Huang & Viraktamath, 1993 and M. jozankeana (Matsumura, 1912) are redescribed based on examination of specimens from mainland China and adjacent territories of Russia respectively; translation of the original description of M. rubrosternalis Kuoh, 1992 from Chinese is provided, also a key to species of Oak-dwelling Macropsis from China is present.
Assuntos
Hemípteros/anatomia & histologia , Hemípteros/classificação , Quercus/fisiologia , Animais , China , Demografia , Ecossistema , Hemípteros/fisiologia , Especificidade da EspécieRESUMO
The purpose of this paper is to validate 4 generic names and 34 specific names previously introduced in the Deltocephalinae from China (Hemiptera: Cicadellidae) by Li, Dai & Xing (2011). The names are unavailable in the original publication, because of the missing information on the type specimen repository. The following genera and species are introduced as new in this publication: Bambusananus, Li & Xing; Branchana Li; Cyclevertex Li & Xing; Lineana Li & Xing; Abrus biprocessus Li; Abrus graciaedeagus Li; Bambusana biflaka Li; Bambusana nigrimaculata Li; Bambusananus furcatus Li & Xing; Branchana xanthota Li; Cyclevertex furcatum Li & Xing; Lineana albipunctata Li & Xing; Lineana ductaedeagusa Li & Xing; Protensus nigrifrons Li & Xing; Protensus yanheensis Li & Xing; Paramesodes menghaiensis Xing & Li; Yuanamia producta (Xing & Li, 2011); Hishimonoides brevis Li, 2011; Litura tripunctata Li; Changwhania huajiangensis Xing & Li; Elginus productus Xing & Li; Metalimnus maoershanensis Xing & Li; Nicolaus bihamatus Xing & Li; Paralaevicephalus bisubulatus Xing & Li; Paralaevicephalus brevissimus Xing & Li; Paralaevicephalus spinosus Xing & Li; Scaphoideus annulatus Li; Scaphoideus bannaensis Li; Longicornus longus Xing & Li; Melanetettix mengyangensis Xing & Li; Osbornellus aurantius Xing & Li; Osbornellus suiyangensis Xing & Li; Osbornellus conoideus Xing & Li; Phlogothamnus acutaedeagus Li; Phlogothamnus luteoguttatus Li; Phlogothamnus productus Li & Xing; Phlogothamnus rugosus Li; Phlogotettix fanjingshanensis Li.
Assuntos
Besouros , Hemípteros , Animais , ChinaRESUMO
The Chinese leafhopper species of the genus Scaphomonus Viraktamath are reviewed, and one new species Scaphomonus furcatus sp. nov. is described and illustrated. A key is given to distinguish Chinese species of the genus. The type specimens of the new species are deposited in the Institute of Entomology, Guizhou University, Guiyang, China (GUGC).
Assuntos
Hemípteros/classificação , Distribuição Animal , Estruturas Animais/anatomia & histologia , Animais , China , Feminino , Hemípteros/anatomia & histologia , MasculinoRESUMO
Two new species, Empoascanara conchata, E. longiaedeaga spp. nov. from Yunnan are described and illustrated, and a key to the species recorded from China is provided.
Assuntos
Hemípteros/classificação , Distribuição Animal , Estruturas Animais/anatomia & histologia , Animais , China , Ecossistema , Feminino , Hemípteros/anatomia & histologia , MasculinoRESUMO
A new replacement name Angustuma nom. nov. is proposed for the leafhopper genus Angustella Li, 1986 of the subfamily Evacanthinae (Hemiptera: Cicadellidae), and twelve new combinations are proposed. A new species Angustuma rudorsuma sp. nov. is described and illustrated from China. A key is given to distinguish all species of the genus. The type specimens of the new species are deposited in the Institute of Entomology, Guizhou University, Guiyang, China (GUGC).
Assuntos
Hemípteros/anatomia & histologia , Hemípteros/classificação , Animais , China , Feminino , MasculinoRESUMO
A new genus of tribe Erythroneurini from China, Laciniata gen. nov. is described and illustrated based on type species L. lijianga sp. nov.
Assuntos
Hemípteros/classificação , Estruturas Animais/anatomia & histologia , Estruturas Animais/crescimento & desenvolvimento , Animais , Tamanho Corporal , China , Hemípteros/anatomia & histologia , Hemípteros/crescimento & desenvolvimento , Masculino , Tamanho do ÓrgãoRESUMO
In the present paper, nine new species, Arboridia anteoculara, A. baiyunensis, A. reniformis, A. lunula, A. cuihuashana, A. paraprocessa, A. echinata, A. tridentata, A. zhenyuana spp. n. and a new record, A. agrillacea from China, are described and illustrated and a key for identification of Chinese species is provided.
Assuntos
Hemípteros/anatomia & histologia , Hemípteros/classificação , Animais , China , Feminino , MasculinoRESUMO
The bamboo-feeding species of tribe Evacanthini are reviewed. They include 9 genera and 13 species: Angustella leucostriata Li & Wang, 1991, Boundarus nigronotus Zhang, Zhang & Wei, 2010a, Carinata kelloggii (Baker, 1923), C. nigrofasciata Li & Wang, 1994a, Convexana fleura Chen, Yang & Li, 2012, Evacanthus repexus Distant, 1908, Onukia guttata Li & Wang, 1991, O. nigra Li & Wang, 1991, Parapythatnus suiyangensis Li & Li, 2011, Taperus fasciatus Li & Wang, 1994b, T. luchunensis Zhang, Zhang & Wei, 2010b and the two new species, Bundera bambusana sp. nov. and Paraonukia wangnioensis sp. nov. The new species are described and all the species are photographed and illustrated. A key to these 13 species is also given.
Assuntos
Hemípteros/classificação , Animais , China , Feminino , Cadeia Alimentar , Hemípteros/anatomia & histologia , Hemípteros/fisiologia , Masculino , PoaceaeRESUMO
The bamboo-feeding species of genus Scaphoideus Uhler (Hemiptera: Cicadellidae: Deltocephalinae) from China are reviewed to include 7 species: S. conicaplateus Li & Dai, 2004 (China: Guizhou), S. fanjingensis Li & Dai, 2004 (China: Guizhou), S. festivus Matsumura, 1902 (China: Guizhou, Yunnan, Sichuan, Shaanxi, Ningxia, Hunan, Beijing, Hebei, Henan, Jiangxi, Fujian, Guangdong, Guangxi, Hainan and Taiwan; India; Sri Lanka; Japan; Korea), S. kumamotonis Matsumura, 1914 (China: Guizhou, Yunnan, Tibet, Sichuan, Zhejiang and Henan; Japan), S. nigrigenatus Li, 1990 (China: Guizhou, Sichuan and Hubei), S. nigrivalveus Li & Wang, 2005 (China: Guizhou and Hubei) and S. yaanensis sp. nov. (China: Sichuan). All seven species are re-illustrated and photographed. The new species is described. A key to the bamboo-feeding species of Scaphoideus is also provided.
Assuntos
Hemípteros/anatomia & histologia , Hemípteros/classificação , Animais , China , Feminino , Cadeia Alimentar , Hemípteros/fisiologia , Masculino , Poaceae , Especificidade da EspécieRESUMO
A new monobasic subgenus, Macropsis (Spinoniacropsis) subgen. nov., of the subfamily Macropsinae (Hemiptera: Auchenorrhyncha: Cicadellidae) based on type species Macropsis flavovirens Kuoh, 1992 from Yunnan Province of China is proposed. The new subgenus can be distinguished by the unique character of the male pygofer with two spinelike processes on the caudal margin. Macropsis (S.)flavovirens is redescribed and illustrated, and data on its geographical distribution are given.
Assuntos
Hemípteros/classificação , Distribuição Animal , Estruturas Animais/anatomia & histologia , Estruturas Animais/crescimento & desenvolvimento , Animais , Tamanho Corporal , China , Feminino , Hemípteros/anatomia & histologia , Hemípteros/crescimento & desenvolvimento , Masculino , Tamanho do ÓrgãoRESUMO
Parathlasia gen. nov., a new leafhopper genus and species of Ledrini, P.guizhouensis sp. nov., from Guizhou, China are described. Morphological differences between the new genus to other related Chinese genera are discussed. A key to distinguish Parathlasia from other similar genera is given.
RESUMO
The green rice leafhopper, Nephotettix cincticeps (Uhler), is an important rice pest and a vector of the rice dwarf virus in Asia. Here, we produced a high-quality chromosome-level genome assembly of 753.23 Mb using PacBio (â¼110×) and Hi-C data (â¼94×). It contained 163 scaffolds and 950 contigs, whose scaffold/contig N50 lengths reached 85.36/2.57 Mb. And 731.19 Mb (97.07%) of the assembly was anchored into eight pseudochromosomes. Genome completeness was attained to 97.0% according to the insect reference Benchmarking Universal Single-Copy Orthologs (BUSCO) gene set (n = 1,367). We masked 347.10 Mb (46.08%) of the genome as repetitive elements. Nine hundred sixty-two noncoding RNAs were identified and 14,337 protein-coding genes were predicted. We also assigned GO term and KEGG pathway annotations for 10,049 and 9,251 genes, respectively. Significantly expanded gene families were primarily involved in immunity, cuticle, digestion, detoxification, and embryonic development. This study provided a crucial genomic resource for better understanding on the biology and evolution in family Cicadellidae.