Detalhe da pesquisa
1.
Bazedoxifene Suppresses the Growth of Osteosarcoma Cells by Inhibiting IL-6 and IL-11/GP130 Signaling Pathway.
J Pediatr Hematol Oncol
; 46(1): 8-14, 2024 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37962127
2.
Carbohydrate-Small Molecule Hybrids as Lead Compounds Targeting IL-6 Signaling.
Molecules
; 28(2)2023 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36677735
3.
Inhibition of Interleukin-6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice.
J Cell Mol Med
; 24(8): 4748-4761, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32164044
4.
LLY17, a novel small molecule STAT3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer.
Breast Cancer Res Treat
; 181(1): 31-41, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32240456
5.
Bazedoxifene exhibits growth suppressive activity by targeting interleukin-6/glycoprotein 130/signal transducer and activator of transcription 3 signaling in hepatocellular carcinoma.
Cancer Sci
; 110(3): 950-961, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30648776
6.
Bazedoxifene is a novel IL-6/GP130 inhibitor for treating triple-negative breast cancer.
Breast Cancer Res Treat
; 175(3): 553-566, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-30852762
7.
Inhibition of IL-6/STAT3 signaling in human cancer cells using Evista.
Biochem Biophys Res Commun
; 491(1): 159-165, 2017 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28711499
8.
A novel small molecular STAT3 inhibitor, LY5, inhibits cell viability, cell migration, and angiogenesis in medulloblastoma cells.
J Biol Chem
; 290(6): 3418-29, 2015 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25313399
9.
Design, synthesis and evaluation of XZH-5 analogues as STAT3 inhibitors.
Bioorg Med Chem
; 23(6): 1348-55, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25698618
10.
CDK4/6 inhibitors in lung cancer: current practice and future directions.
Eur Respir Rev
; 33(171)2024 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38355149
11.
Polarization of Cancer-Associated Macrophages Maneuver Neoplastic Attributes of Pancreatic Ductal Adenocarcinoma.
Cancers (Basel)
; 15(13)2023 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37444617
12.
A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells.
Int J Cancer
; 130(6): 1459-69, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21520044
13.
Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice.
Invest New Drugs
; 30(3): 916-26, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21340507
14.
Reactivation of RASSF1A in breast cancer cells by curcumin.
Nutr Cancer
; 64(8): 1228-35, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23145775
15.
Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines.
BMC Vet Res
; 8: 244, 2012 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23244668
16.
Breast Cancer Tumor Microenvironment and Molecular Aberrations Hijack Tumoricidal Immunity.
Cancers (Basel)
; 14(2)2022 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35053449
17.
Combined inhibition of IL6 and IL8 pathways suppresses ovarian cancer cell viability and migration and tumor growth.
Int J Oncol
; 60(5)2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35315502
18.
LLL12B, a Novel Small-Molecule STAT3 Inhibitor, Induces Apoptosis and Suppresses Cell Migration and Tumor Growth in Triple-Negative Breast Cancer Cells.
Biomedicines
; 10(8)2022 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36009550
19.
Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells.
J Biol Chem
; 285(35): 27429-27439, 2010 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20562100
20.
Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells.
Cancer Sci
; 102(7): 1381-7, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21435102