Detalhe da pesquisa
1.
IKKß promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3.
Genes Dev
; 30(16): 1837-51, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27585591
2.
The B56α subunit of PP2A is necessary for mesenchymal stem cell commitment to adipocyte.
EMBO Rep
; 22(8): e51910, 2021 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34232566
3.
Glutamine deficiency induces DNA alkylation damage and sensitizes cancer cells to alkylating agents through inhibition of ALKBH enzymes.
PLoS Biol
; 15(11): e2002810, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29107960
4.
The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose.
Mol Cell
; 40(5): 823-33, 2010 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21145489
5.
Vemurafenib resistance reprograms melanoma cells towards glutamine dependence.
J Transl Med
; 13: 210, 2015 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26139106
6.
Alpha-Ketoglutarate Regulates Tnfrsf12a/Fn14 Expression via Histone Modification and Prevents Cancer-Induced Cachexia.
Genes (Basel)
; 14(9)2023 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37761958
7.
Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.
Nat Commun
; 11(1): 3326, 2020 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32620791
8.
α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer.
Nat Cancer
; 1(3): 345-358, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32832918
9.
p53 Promotes Cancer Cell Adaptation to Glutamine Deprivation by Upregulating Slc7a3 to Increase Arginine Uptake.
Cell Rep
; 26(11): 3051-3060.e4, 2019 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30865893
10.
MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1.
Nat Commun
; 10(1): 809, 2019 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30778058
11.
IKKß activates p53 to promote cancer cell adaptation to glutamine deprivation.
Oncogenesis
; 7(11): 93, 2018 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30478303
12.
Molecular Pathways: Metabolic Control of Histone Methylation and Gene Expression in Cancer.
Clin Cancer Res
; 23(15): 4004-4009, 2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28404599
13.
Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation.
Nat Cell Biol
; 18(10): 1090-101, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27617932