Detalhe da pesquisa
1.
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Cell
; 179(2): 417-431.e19, 2019 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31585081
2.
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Cell
; 180(2): 406, 2020 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31978350
3.
Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development.
J Transl Med
; 19(1): 517, 2021 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34930320
4.
Fab-Nanolipoprotein Conjugate Causes Vitreous Opacity and Cataracts Following a Single Intravitreal Administration in New Zealand White Rabbits.
Toxicol Pathol
; 49(3): 647-655, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33733956
5.
Retinal and Lens Degeneration in New Zealand White Rabbits Administered Intravitreal TSG-6 Link Domain-Rabbit FAb Fusion Proteins.
Toxicol Pathol
; 49(3): 634-646, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33349160
6.
Novel antibody-antibiotic conjugate eliminates intracellular S. aureus.
Nature
; 527(7578): 323-8, 2015 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26536114
7.
Hyaluronic Acid-Antibody Fragment Bioconjugates for Extended Ocular Pharmacokinetics.
Bioconjug Chem
; 30(11): 2782-2789, 2019 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31553572
8.
In Vivo Stability Profiles of Anti-factor D Molecules Support Long-Acting Delivery Approaches.
Mol Pharm
; 16(1): 86-95, 2019 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30444371
9.
Corrigendum to "A novel method to produce synthetic murine CXCL10 for efficient screening of functional variants" [Bioorg. Chem. 116 (2021) 105376].
Bioorg Chem
; 120: 105655, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35134644
10.
A mechanistic pharmacokinetic/pharmacodynamic model of factor D inhibition in cynomolgus monkeys by lampalizumab for the treatment of geographic atrophy.
J Pharmacol Exp Ther
; 355(2): 288-96, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26359312
11.
Complement inhibition in cynomolgus monkeys by anti-factor d antigen-binding fragment for the treatment of an advanced form of dry age-related macular degeneration.
J Pharmacol Exp Ther
; 351(3): 527-37, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25232192
12.
Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
Sci Transl Med
; 14(675): eabp9159, 2022 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36516271
13.
Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema.
Transl Vis Sci Technol
; 11(10): 27, 2022 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36255358
14.
A homogeneous high-DAR antibody-drug conjugate platform combining THIOMAB antibodies and XTEN polypeptides.
Chem Sci
; 13(11): 3147-3160, 2022 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35414872
15.
Dramatic activation of an antibody by a single amino acid change in framework.
Sci Rep
; 11(1): 22365, 2021 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34785671
16.
Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate.
mBio
; 12(3): e0020221, 2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34061593
17.
Pharmacokinetics of humanized monoclonal anti-tumor necrosis factor-{alpha} antibody and its neonatal Fc receptor variants in mice and cynomolgus monkeys.
Drug Metab Dispos
; 38(4): 600-5, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20071453
18.
Bivalent antibody pliers inhibit ß-tryptase by an allosteric mechanism dependent on the IgG hinge.
Nat Commun
; 11(1): 6435, 2020 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33353951
19.
Influence of Charge, Hydrophobicity, and Size on Vitreous Pharmacokinetics of Large Molecules.
Transl Vis Sci Technol
; 8(6): 1, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31695962
20.
Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.
PLoS One
; 14(6): e0218613, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31251757