Detalhe da pesquisa
1.
Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study.
Eur Respir J
; 59(6)2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34824054
2.
Combined Blockade of TNF-α and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice.
J Immunol
; 202(7): 2017-2026, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30745461
3.
I_MDS: an inflammatory bowel disease molecular activity score to classify patients with differing disease-driving pathways and therapeutic response to anti-TNF treatment.
PLoS Comput Biol
; 15(4): e1006951, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31039157
4.
Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation.
J Allergy Clin Immunol
; 143(2): 577-590, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29902480
5.
"T2-high" in severe asthma related to blood eosinophil, exhaled nitric oxide and serum periostin.
Eur Respir J
; 53(1)2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30578390
6.
Contribution of airway eosinophils in airway wall remodeling in asthma: Role of MMP-10 and MET.
Allergy
; 74(6): 1102-1112, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30667542
7.
Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma.
J Allergy Clin Immunol
; 141(2): 560-570, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28528200
8.
Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis.
Eur Respir J
; 51(5)2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29650557
9.
Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis: results of a multicentre, double-blind, randomised-withdrawal trial.
Ann Rheum Dis
; 77(1): 21-29, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28507219
10.
A phase 2a study of toreforant, a histamine H4 receptor antagonist, in eosinophilic asthma.
Ann Allergy Asthma Immunol
; 121(5): 568-574, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30102965
11.
A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED.
Am J Respir Crit Care Med
; 195(4): 443-455, 2017 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27580351
12.
Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients.
J Allergy Clin Immunol
; 140(3): 710-719, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28089872
13.
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics.
J Allergy Clin Immunol
; 139(6): 1797-1807, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27773852
14.
T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED.
Eur Respir J
; 49(2)2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28179442
15.
Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma.
Eur Respir J
; 50(3)2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28954779
16.
Instability of sputum molecular phenotypes in U-BIOPRED severe asthma.
Eur Respir J
; 57(2)2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33008937
17.
Severe asthma exists despite suppressed tissue inflammation: findings of the U-BIOPRED study.
Eur Respir J
; 48(5): 1307-1319, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27799384
18.
Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study.
Respir Res
; 17(1): 165, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27978840
19.
Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics.
Allergy
; 76(1): 380-383, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32865817
20.
Sirukumab and adalimumab reduce power Doppler ultrasound signal in patients with rheumatoid arthritis by 4 weeks in a phase III trial.
Ann Rheum Dis
; 78(10): 1439-1441, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31018960