1.
J Org Chem
; 85(21): 13655-13663, 2020 11 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33045828
RESUMO
An efficient one-pot synthesis of oxazolidinones was developed through CuI/DBU/MS joint system-catalyzed carboxylative cyclization of arylacetylene, arylaldehyde, and arylamine in water medium under a 1 atm carbon dioxide (CO2) atmosphere. The 4 Å molecular sieves (MSs) were added to improve CO2 capture and facilitate carboxylation to give the products in high yields. The CuI/DBU/MS system is robust and highly effective for the reactions with different substrates, and some target products were obtained in an excellent yield of â¼96%, with no side products in the final step.