Detalhe da pesquisa
1.
Dual role of interleukin-1ß in islet amyloid formation and its ß-cell toxicity: Implications for type 2 diabetes and islet transplantation.
Diabetes Obes Metab
; 19(5): 682-694, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28058779
2.
IDO-Expressing Fibroblasts Protect Islet Beta Cells From Immunological Attack and Reverse Hyperglycemia in Non-Obese Diabetic Mice.
J Cell Physiol
; 231(9): 1964-73, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26743772
3.
The role of caspase-8 in amyloid-induced beta cell death in human and mouse islets.
Diabetologia
; 57(4): 765-75, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24442508
4.
Three-dimensional scaffolds reduce islet amyloid formation and enhance survival and function of cultured human islets.
Am J Pathol
; 181(4): 1296-305, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22902430
5.
The role of mitochondrial apoptotic pathway in islet amyloid-induced ß-cell death.
Mol Cell Endocrinol
; 537: 111424, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34400259
6.
Pancreatic ß cell-selective zinc transporter 8 insufficiency accelerates diabetes associated with islet amyloidosis.
JCI Insight
; 6(10)2021 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34027899
7.
Amyloid formation reduces protein kinase B phosphorylation in primary islet ß-cells which is improved by blocking IL-1ß signaling.
PLoS One
; 13(2): e0193184, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29474443
8.
Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death.
Diabetes
; 55(8): 2192-201, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16873681
9.
Amyloid formation disrupts the balance between interleukin-1ß and interleukin-1 receptor antagonist in human islets.
Mol Metab
; 6(8): 833-844, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28752047
10.
Processing of pro-islet amyloid polypeptide in the constitutive and regulated secretory pathways of beta cells.
Mol Endocrinol
; 19(8): 2154-63, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15802374
11.
Role of carboxypeptidase E in processing of pro-islet amyloid polypeptide in {beta}-cells.
Endocrinology
; 146(4): 1808-17, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15618358
12.
Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide.
Diabetes
; 53(1): 141-8, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14693708
13.
Mechanisms by which bis(maltolato)oxovanadium(IV) normalizes phosphoenolpyruvate carboxykinase and glucose-6-phosphatase expression in streptozotocin-diabetic rats in vivo.
Endocrinology
; 143(12): 4636-45, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12446591
14.
Islet amyloid polypeptide and type 2 diabetes.
Exp Gerontol
; 38(4): 347-51, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12670620
15.
Erratum. Small Interfering RNA-Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Diabetes 2008;57:3045-3055.
Diabetes
; 65(3): 818, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908907
16.
New insights into the mechanisms of islet inflammation in type 2 diabetes.
Diabetes
; 64(4): 1094-6, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25805760
17.
Cleavage of protein kinase D after acute hypoinsulinemia prevents excessive lipoprotein lipase-mediated cardiac triglyceride accumulation.
Diabetes
; 58(11): 2464-75, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19875622
18.
Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture.
Diabetes
; 57(11): 3045-55, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18694973
19.
Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide.
Am J Physiol Endocrinol Metab
; 286(3): E418-24, 2004 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-14613923