1.
J Org Chem
; 76(11): 4661-4, 2011 Jun 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21517112
RESUMO
A series of simple chiral primary amino acids were first successfully applied to promote the enantioselective α-amination of branched aldehydes with azadicarboxylates and the desired adducts bearing quaternary stereogenic centers were obtained in excellent yields (up to 99%) and enantioselectivities (up to 97% ee).