Detalhe da pesquisa
1.
Discovery of fluorobenzimidazole HCV NS5A inhibitors.
Bioorg Med Chem Lett
; 26(22): 5462-5467, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27780635
2.
In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor.
Antimicrob Agents Chemother
; 59(3): 1505-11, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25534735
3.
High potency improvements to weak aryl uracil HCV polymerase inhibitor leads.
Bioorg Med Chem Lett
; 23(15): 4367-9, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23791079
4.
Aryl uracil inhibitors of hepatitis C virus NS5B polymerase: synthesis and characterization of analogs with a fused 5,6-bicyclic ring motif.
Bioorg Med Chem Lett
; 23(12): 3487-90, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23664214
5.
Interviews with Indian Animal Shelter Staff: Similarities and Differences in Challenges and Resiliency Factors Compared to Western Counterparts.
Animals (Basel)
; 12(19)2022 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36230303
6.
Wild Zebrafish Sentinels: Biological Monitoring of Site Differences Using Behavior and Morphology.
Toxics
; 9(7)2021 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34357908
7.
Temporal and environmental drivers of fish-community structure in tropical streams from two contrasting regions in India.
PLoS One
; 15(4): e0227354, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32271767
8.
Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral Bioavailability.
J Med Chem
; 61(3): 1153-1163, 2018 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29342358
9.
Highlights of the Structure-Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530).
J Med Chem
; 61(9): 4052-4066, 2018 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29653491
10.
A replicon-based shuttle vector system for assessing the phenotype of HCV NS5B polymerase genes isolated from patient populations.
J Virol Methods
; 145(2): 137-45, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17604129
11.
Discovery of ABT-267, a pan-genotypic inhibitor of HCV NS5A.
J Med Chem
; 57(5): 2047-57, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24400777
12.
Development of a cell-based assay for high-throughput screening of inhibitors against HCV genotypes 1a and 1b in a single well.
Antiviral Res
; 82(1): 82-8, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19174175
13.
Synthesis and biological characterization of B-ring amino analogues of potent benzothiadiazine hepatitis C virus polymerase inhibitors.
J Med Chem
; 52(10): 3174-83, 2009 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19402666
14.
Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology.
Hepatology
; 45(6): 1413-21, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17518369
15.
Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro.
Antimicrob Agents Chemother
; 49(10): 4305-14, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16189112