Detalhe da pesquisa
1.
Nitric oxide prevents atorvastatin-induced skeletal muscle dysfunction and alterations in mice.
Muscle Nerve
; 47(1): 72-80, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23042511
2.
NCX 4040, a nitric oxide-donating aspirin, exerts anti-inflammatory effects through inhibition of I kappa B-alpha degradation in human monocytes.
J Immunol
; 184(4): 2140-7, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20065114
3.
The cardio-protective properties of Ncx-6550, a nitric oxide donating pravastatin, in the mouse.
Microcirculation
; 17(6): 417-26, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20690980
4.
Biaryl and heteroaryl derivatives of SCH 58261 as potent and selective adenosine A2A receptor antagonists.
Bioorg Med Chem Lett
; 18(14): 4199-203, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18562199
5.
NCX 6560, a nitric oxide-releasing derivative of atorvastatin, inhibits cholesterol biosynthesis and shows anti-inflammatory and anti-thrombotic properties.
Eur J Pharmacol
; 570(1-3): 115-24, 2007 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-17632098
6.
Persistent behavioral sensitization to chronic L-DOPA requires A2A adenosine receptors.
J Neurosci
; 22(3): 1054-62, 2002 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-11826134
7.
Nitric oxide-releasing aspirin derivative, NCX 4016, promotes reparative angiogenesis and prevents apoptosis and oxidative stress in a mouse model of peripheral ischemia.
Arterioscler Thromb Vasc Biol
; 24(11): 2082-7, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15345513
8.
Sensitivity to selective adenosine A1 and A2A receptor antagonists of the release of glutamate induced by ischemia in rat cerebrocortical slices.
Neuropharmacology
; 45(2): 201-10, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12842126
9.
7-Substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: a study on the importance of modifications at the side chain on the activity and solubility.
J Med Chem
; 45(1): 115-26, 2002 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-11754583
10.
Effects of adenosine A1 and A2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes.
Br J Pharmacol
; 136(3): 434-40, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12023946
11.
The selective A2A receptor antagonist SCH 58261 reduces striatal transmitter outflow, turning behavior and ischemic brain damage induced by permanent focal ischemia in the rat.
Brain Res
; 959(2): 243-50, 2003 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12493612
12.
Effects of A(1) and A(2A) adenosine receptor ligands in mouse acute models of pain.
Neurosci Lett
; 328(3): 241-4, 2002 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-12147316
13.
Nitric oxide enhances the anti-inflammatory and anti-atherogenic activity of atorvastatin in a mouse model of accelerated atherosclerosis.
Cardiovasc Res
; 94(3): 428-38, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22362817
14.
Treatment with a nitric oxide-donating NSAID alleviates functional muscle ischemia in the mouse model of Duchenne muscular dystrophy.
PLoS One
; 7(11): e49350, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23139842
15.
3H-[1,2,4]-Triazolo[5,1-i]purin-5-amine derivatives as adenosine A2A antagonists.
Bioorg Med Chem Lett
; 17(6): 1659-62, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17234414
16.
Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy.
Proc Natl Acad Sci U S A
; 104(1): 264-9, 2007 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17182743
17.
Potent, selective, and orally active adenosine A2A receptor antagonists: arylpiperazine derivatives of pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines.
Bioorg Med Chem Lett
; 17(5): 1376-80, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17236762
18.
Nitric oxide (NO)-releasing statin derivatives, a class of drugs showing enhanced antiproliferative and antiinflammatory properties.
Proc Natl Acad Sci U S A
; 101(22): 8497-502, 2004 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15173604