Detalhe da pesquisa
1.
BET inhibition induces synthetic lethality in PTEN deficient colorectal cancers via dual action on p21CIP1/WAF1.
Int J Biol Sci
; 20(6): 1978-1991, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38617536
2.
MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism.
Int J Biol Sci
; 19(11): 3544-3557, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37496993
3.
ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones.
Int J Biol Sci
; 19(13): 4020-4035, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37705743
4.
Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation.
Oncogene
; 41(19): 2734-2748, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35393542
5.
Natural products targeting cancer cell dependency.
J Antibiot (Tokyo)
; 74(10): 677-686, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34163025
6.
Aurora kinase A, a synthetic lethal target for precision cancer medicine.
Exp Mol Med
; 53(5): 835-847, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050264
7.
Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression.
Oncogene
; 40(5): 937-950, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33293694
8.
Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT.
Int J Biol Sci
; 16(11): 1774-1784, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32398948
9.
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics.
Nat Commun
; 11(1): 5105, 2020 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037191