Detalhe da pesquisa
1.
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera.
Proc Natl Acad Sci U S A
; 121(2): e2306682120, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38181056
2.
Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration.
PLoS Genet
; 18(4): e1010138, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35404932
3.
Therapeutics in the Pipeline Targeting α-Synuclein for Parkinson's Disease.
Pharmacol Rev
; 74(1): 207-237, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35017177
4.
Experimental Neurotherapeutics: Surfing the Tidal Wave of New Opportunities.
Ann Neurol
; 93(3): 427-430, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36546649
5.
Pathogenetic Contributions and Therapeutic Implications of Transglutaminase 2 in Neurodegenerative Diseases.
Int J Mol Sci
; 25(4)2024 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38397040
6.
Parkinson Disease and Subthalamic Nucleus Deep Brain Stimulation: Cognitive Effects in GBA Mutation Carriers.
Ann Neurol
; 91(3): 424-435, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34984729
7.
Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA.
Proc Natl Acad Sci U S A
; 117(3): 1457-1467, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31900363
8.
Role of striatal ΔFosB in l-Dopa-induced dyskinesias of parkinsonian nonhuman primates.
Proc Natl Acad Sci U S A
; 116(37): 18664-18672, 2019 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31455727
9.
Striatal ΔFosB gene suppression inhibits the development of abnormal involuntary movements induced by L-Dopa in rats.
Gene Ther
; 28(12): 760-770, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33707771
10.
Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics.
Part Fibre Toxicol
; 18(1): 42, 2021 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34819099
11.
Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB.
Proc Natl Acad Sci U S A
; 115(51): E12053-E12062, 2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30509990
12.
Fostering Academia-Industry Partnerships to Facilitate Therapeutic Discoveries in Neurology: The Role of ANA as a Catalyst.
Ann Neurol
; 95(5): 825-826, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38436546
13.
Reply to: Cognitive Effects of Deep Brain Stimulation in GBA-Related Parkinson's Disease.
Ann Neurol
; 92(2): 345-346, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35687082
14.
Regulation of Signal Transduction by DJ-1.
Adv Exp Med Biol
; 1037: 97-131, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29147906
15.
MicroRNA-7 Promotes Glycolysis to Protect against 1-Methyl-4-phenylpyridinium-induced Cell Death.
J Biol Chem
; 290(19): 12425-34, 2015 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25814668
16.
Dual κ-agonist/µ-antagonist opioid receptor modulation reduces levodopa-induced dyskinesia and corrects dysregulated striatal changes in the nonhuman primate model of Parkinson disease.
Ann Neurol
; 77(6): 930-41, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25820831
17.
MicroRNA-7 protects against 1-methyl-4-phenylpyridinium-induced cell death by targeting RelA.
J Neurosci
; 34(38): 12725-37, 2014 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25232110
18.
Transglutaminase 2 exacerbates α-synuclein toxicity in mice and yeast.
FASEB J
; 28(10): 4280-91, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24970392
19.
DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway.
Hum Mol Genet
; 21(13): 3013-24, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22492997
20.
NIH Toolbox performance of persons with Parkinson's disease according to GBA1 and STN-DBS status.
Ann Clin Transl Neurol
; 11(4): 899-904, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38337113