Detalhe da pesquisa
1.
Mutant Phosphodiesterase 3A Protects From Hypertension-Induced Cardiac Damage.
Circulation
; 146(23): 1758-1778, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36259389
2.
Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2.
Circ Res
; 117(8): 707-19, 2015 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26243800
3.
Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2.
J Biol Chem
; 290(11): 6763-76, 2015 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25593322
4.
Luteinizing Hormone Causes Phosphorylation and Activation of the cGMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the Resumption of Meiosis.
Biol Reprod
; 94(5): 110, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27009040
5.
Selective regulation of cyclic nucleotide phosphodiesterase PDE3A isoforms.
Proc Natl Acad Sci U S A
; 110(49): 19778-83, 2013 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24248367
6.
New pharmacologic interventions to increase cardiac contractility: challenges and opportunities.
Curr Opin Cardiol
; 30(3): 285-91, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25807221
7.
Phosphodiesterase type 3A regulates basal myocardial contractility through interacting with sarcoplasmic reticulum calcium ATPase type 2a signaling complexes in mouse heart.
Circ Res
; 112(2): 289-97, 2013 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23168336
8.
Phosphodiesterase 4D regulates baseline sarcoplasmic reticulum Ca2+ release and cardiac contractility, independently of L-type Ca2+ current.
Circ Res
; 109(9): 1024-1030, 2011 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21903937
9.
Conserved expression and functions of PDE4 in rodent and human heart.
Basic Res Cardiol
; 106(2): 249-62, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21161247
10.
Phosphodiesterase inhibition in heart failure.
Handb Exp Pharmacol
; (204): 237-49, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21695643
11.
cGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium.
J Pharmacol Exp Ther
; 330(3): 884-91, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19546307
12.
Combined use of PDE5 inhibitors and nitrates in the treatment of pulmonary arterial hypertension in patients with heart failure.
J Card Fail
; 15(1): 31-4, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19181291
13.
Phosphodiesterase inhibition in heart failure.
Heart Fail Rev
; 14(4): 255-63, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19096931
14.
cAMP and cGMP signaling cross-talk: role of phosphodiesterases and implications for cardiac pathophysiology.
Circ Res
; 100(11): 1569-78, 2007 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17556670
15.
A PDE3A Promoter Polymorphism Regulates cAMP-Induced Transcriptional Activity in Failing Human Myocardium.
J Am Coll Cardiol
; 73(10): 1173-1184, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30871701
16.
Combination therapy with beta-adrenergic receptor antagonists and phosphodiesterase inhibitors for chronic heart failure.
Pharmacotherapy
; 28(12): 1523-30, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19025433
17.
Functions of PDE3 Isoforms in Cardiac Muscle.
J Cardiovasc Dev Dis
; 5(1)2018 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29415428
18.
Multiple cAMP Phosphodiesterases Act Together to Prevent Premature Oocyte Meiosis and Ovulation.
Endocrinology
; 159(5): 2142-2152, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29608743
19.
Discovery of Potent and Selective Periphery-Restricted Quinazoline Inhibitors of the Cyclic Nucleotide Phosphodiesterase PDE1.
J Med Chem
; 61(10): 4635-4640, 2018 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29718668
20.
Novel approaches to targeting PDE3 in cardiovascular disease.
Pharmacol Ther
; 163: 74-81, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27108947