Tactile Routing for Location Privacy Preservation in Wireless Sensor Networks: A Game Theoretic Approach.

Location Privacy Preservation (LPP) in Wireless Sensor Networks (WSNs) during the era of the Internet of things and smart systems is a critical element in the success of WSNs. LPP in WSN can be stated as: given a WSN with an adversary aiming to unravel the location of critical nodes of a WSN, the goal of the WSN manager is to enshroud the location of the critical nodes via routing and/or encryption mechanisms. Typical research in the LPP of WSN routing involves developing and/or estimating the performance of a fixed routing protocol under a given attack mechanism. Motivated by advancements in network softwarization, in this work, we propose an approach where the WSN manager as well as the WSN adversary can deploy multiple routing and attack mechanisms, respectively. Initially, the proposed approach is formulated as a repeated two-player zero-sum game. The formulation is further extended to handle multiple objectives and incomplete information in the game matrix. In this work, the multiple objectives are handled via the epsilon constraint method. The presence of incomplete information in the formulation is modeled as interval based uncertainty. To sum, the proposed formulation ultimately boils down to linear programming problems, which can be efficiently solved. Numerical case studies to showcase the applicability of the proposed approach are illustrated in this work. Finally, discussion on obtaining the required data from any given WSN, discussion and interpretation of the formulation's results, and future research direction of the current work is presented.

Big Data Blind Separation.

Data or signal separation is one of the critical areas of data analysis. In this work, the problem of non-negative data separation is considered. The problem can be briefly described as follows: given X ∈ R m × N , find A ∈ R m × n and S ∈ R + n × N such that X = A S . Specifically, the problem with sparse locally dominant sources is addressed in this work. Although the problem is well studied in the literature, a test to validate the locally dominant assumption is not yet available. In addition to that, the typical approaches available in the literature sequentially extract the elements of the mixing matrix. In this work, a mathematical modeling-based approach is presented that can simultaneously validate the assumption, and separate the given mixture data. In addition to that, a correntropy-based measure is proposed to reduce the model size. The approach presented in this paper is suitable for big data separation. Numerical experiments are conducted to illustrate the performance and validity of the proposed approach.

Functional modelling of an equine bronchoalveolar lavage fluid proteome provides experimental confirmation and functional annotation of equine genome sequences.

The equine genome sequence enables the use of high-throughput genomic technologies in equine research, but accurate identification of expressed gene products and interpreting their biological relevance require additional structural and functional genome annotation. Here, we employ the equine genome sequence to identify predicted and known proteins using proteomics and model these proteins into biological pathways, identifying 582 proteins in normal cell-free equine bronchoalveolar lavage fluid (BALF). We improved structural and functional annotation by directly confirming the in vivo expression of 558 (96%) proteins, which were computationally predicted previously, and adding Gene Ontology (GO) annotations for 174 proteins, 108 of which lacked functional annotation. Bronchoalveolar lavage is commonly used to investigate equine respiratory disease, leading us to model the associated proteome and its biological functions. Modelling of protein functions using Ingenuity Pathway Analysis identified carbohydrate metabolism, cell-to-cell signalling, cellular function, inflammatory response, organ morphology, lipid metabolism and cellular movement as key biological processes in normal equine BALF. Comparative modelling of protein functions in normal cell-free bronchoalveolar lavage proteomes from horse, human, and mouse, performed by grouping GO terms sharing common ancestor terms, confirms conservation of functions across species. Ninety-one of 92 human GO categories and 105 of 109 mouse GO categories were conserved in the horse. Our approach confirms the utility of the equine genome sequence to characterize protein networks without antibodies or mRNA quantification, highlights the need for continued structural and functional annotation of the equine genome and provides a framework for equine researchers to aid in the annotation effort.