Detalhe da pesquisa
1.
Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in Dementia.
J Am Chem Soc
; 142(18): 8183-8193, 2020 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32233474
2.
Towards an understanding of amyloid-ß oligomers: characterization, toxicity mechanisms, and inhibitors.
Chem Soc Rev
; 46(2): 310-323, 2017 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27878186
3.
Mechanistic Insights into Tunable Metal-Mediated Hydrolysis of Amyloid-ß Peptides.
J Am Chem Soc
; 139(6): 2234-2244, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28098992
4.
Importance of the Dimethylamino Functionality on a Multifunctional Framework for Regulating Metals, Amyloid-ß, and Oxidative Stress in Alzheimer's Disease.
Inorg Chem
; 55(10): 5000-13, 2016 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27119456
5.
Synaptic Copper, Amyloid-ß, and Neurotransmitters in Alzheimer's Disease.
Biochemistry
; 59(1): 15-17, 2020 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31603659
6.
APP-C31: An Intracellular Promoter of Both Metal-Free and Metal-Bound Amyloid-ß40 Aggregation and Toxicity in Alzheimer's Disease.
Adv Sci (Weinh)
; 11(4): e2307182, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37949680
7.
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes.
bioRxiv
; 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38798357
8.
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes.
bioRxiv
; 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38798619
9.
Unveiling the impact of oxidation-driven endogenous protein interactions on the dynamics of amyloid-ß aggregation and toxicity.
Chem Sci
; 14(20): 5340-5349, 2023 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37234895
10.
Conformational and functional changes of the native neuropeptide somatostatin occur in the presence of copper and amyloid-ß.
Nat Chem
; 14(9): 1021-1030, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35817963
11.
Distinct impact of glycation towards the aggregation and toxicity of murine and human amyloid-ß.
Chem Commun (Camb)
; 57(62): 7637-7640, 2021 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34254069
12.
Tunable regulatory activities of 1,10-phenanthroline derivatives towards acid sphingomyelinase and Zn(ii)-amyloid-ß.
Chem Commun (Camb)
; 55(42): 5847-5850, 2019 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31042246
13.
Link of impaired metal ion homeostasis to mitochondrial dysfunction in neurons.
Curr Opin Chem Biol
; 43: 8-14, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29100100
14.
Tailoring Hydrophobic Interactions between Probes and Amyloid-ß Peptides for Fluorescent Monitoring of Amyloid-ß Aggregation.
ACS Omega
; 3(5): 5141-5154, 2018 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31458729
15.
Regulatory Activities of Dopamine and Its Derivatives toward Metal-Free and Metal-Induced Amyloid-ß Aggregation, Oxidative Stress, and Inflammation in Alzheimer's Disease.
ACS Chem Neurosci
; 9(11): 2655-2666, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29782798
16.
A zinc fluorescent sensor used to detect mercury (II) and hydrosulfide.
Spectrochim Acta A Mol Biomol Spectrosc
; 178: 203-211, 2017 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28189093
17.
A PET-based fluorometric chemosensor for the determination of mercury(II) and pH, and hydrolysis reaction-based colorimetric detection of hydrogen sulfide.
Dalton Trans
; 45(13): 5700-12, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26928649
18.
In Cellulo Mapping of Subcellular Localized Bilirubin.
ACS Chem Biol
; 11(8): 2177-85, 2016 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27232847
19.
Stepwise silver-staining-based immunosorbent assay for amyloid-beta autoantibody detection.
Nanomedicine (Lond)
; 3(4): 485-93, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18694311