Detalhe da pesquisa
1.
AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy.
Mol Ther
; 25(12): 2727-2742, 2017 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28882452
2.
MCT1-dependent energetic failure and neuroinflammation underlie optic nerve degeneration in Wolfram syndrome mice.
Elife
; 122023 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36645345
3.
A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development.
Sci Adv
; 8(31): eabn3986, 2022 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921410
4.
Modeling native and seeded Synuclein aggregation and related cellular dysfunctions in dopaminergic neurons derived by a new set of isogenic iPSC lines with SNCA multiplications.
Cell Death Dis
; 13(10): 881, 2022 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36261424
5.
Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity.
Nat Commun
; 12(1): 6237, 2021 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34716339
6.
Author Correction: Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity.
Nat Commun
; 12(1): 7359, 2021 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34916524