RESUMO
This report describes a case of dysgerminoma in a 21-year-old eastern rosella (Platycercus eximius eximius) that presented with dyspnea and a severely distended coelom. The bird was euthanatized, and a large, left-sided coelomic mass was identified. Microscopically, the mass was composed of sheets and nests of round to polygonal neoplastic cells with lacy cytoplasm. The neoplastic cells were weakly positive for vimentin and c-kit but negative for pancytokeratin, AE1, and inhibin. On the basis of the histomorphology and immunoreactivity, the neoplasm was determined to be a dysgerminoma. The variability of histologic appearance and immunohistochemical staining of dysgerminomas in humans compared with veterinary species is discussed.
Assuntos
Doenças das Aves/patologia , Disgerminoma/veterinária , Neoplasias Ovarianas/veterinária , Papagaios , Animais , Disgerminoma/patologia , Feminino , Neoplasias Ovarianas/patologiaRESUMO
An adult, male double yellow-headed Amazon parrot (Amazona ochrocephala oratrix) was diagnosed with chronic lymphocytic leukemia based on results of a complete blood cell count and cytologic examination of a bone marrow aspirate. Treatment with oral chlorambucil was attempted, but no response was evident after 40 days. The bird was euthanatized, and the diagnosis of chronic lymphocytic leukemia was confirmed on gross and microscopic examination of tissues. Neoplastic lymphocytes were found in the bone marrow, liver, kidney, testes, and blood vessels. Based on CD3-positive immunocytochemical and immunohistochemical immunophenotyping, the chronic lymphocytic leukemia was determined to be of T-cell origin.
Assuntos
Amazona , Leucemia de Células T/veterinária , Animais , Antineoplásicos Alquilantes/uso terapêutico , Clorambucila/uso terapêutico , Doença Crônica , Leucemia de Células T/tratamento farmacológico , Leucemia de Células T/patologia , MasculinoRESUMO
This article reviews clinically relevant neuroanatomy of the central nervous system of the domestic rabbit (Oryctolagus cuniculus) that will help guide veterinarians in localizing neurological disease in this species. Although the vertebral column, spinal cord and brain of rabbits are similar to those of other mammals, features unique to the rabbit are emphasized where they exist.
Assuntos
Doenças do Sistema Nervoso Central/veterinária , Sistema Nervoso Central/anatomia & histologia , Coelhos/anatomia & histologia , Animais , Sistema Nervoso Central/fisiologia , Doenças do Sistema Nervoso Central/diagnóstico , Feminino , Masculino , Neuroanatomia , Especificidade da EspécieRESUMO
Completion of a thorough neurological examination of a rabbit is essential for clinicians to determine the location of a neurological problem. Determination of the location of a lesion (whether solitary or multifocal/diffuse) enables a clinician to list the most likely causes of the problem. This article presents the neurological examination of the rabbit, followed by a practical guide to lesion localization in this species.
Assuntos
Técnicas de Diagnóstico Neurológico/veterinária , Doenças do Sistema Nervoso/veterinária , Sistema Nervoso/patologia , Coelhos , Animais , Diagnóstico Diferencial , Feminino , Masculino , Doenças do Sistema Nervoso/diagnóstico , Doenças do Sistema Nervoso/patologia , Fenômenos Fisiológicos do Sistema Nervoso , Neuroanatomia , Exame Neurológico/métodos , Exame Neurológico/veterináriaRESUMO
CASE DESCRIPTION: A 3-month-old red-lored Amazon parrot (Amazona autumnalis autumnalis) was evaluated for severe lethargy. CLINICAL FINDINGS: Avian influenza virus hemagglutinin subtype H5N2 with low pathogenicity was characterized by virus isolation, real-time reverse transcriptase PCR assay, chicken intravenous pathogenicity index, and reference sera. The virus was also determined to be closely related to a virus lineage that had been reported only in Mexico and Central America. TREATMENT AND OUTCOME: The chick was admitted to the hospital and placed in quarantine. Supportive care treatment was administered. Although detection of H5 avian influenza virus in birds in the United States typically results in euthanasia of infected birds, an alternative strategy with strict quarantine measures and repeated diagnostic testing was used. The chick recovered from the initial clinical signs after 4 days and was released from quarantine 9 weeks after initial evaluation after 2 consecutive negative virus isolation and real-time reverse transcriptase PCR assay results. CLINICAL RELEVANCE: To the authors' knowledge, this is the first report of H5N2 avian influenza A virus isolated from a psittacine bird and represents the first introduction of this virus into the United States, most likely by illegal importation of psittacine birds. Avian influenza A virus should be considered as a differential diagnosis for clinical signs of gastrointestinal tract disease in psittacine birds, especially in birds with an unknown history of origin. Although infection with avian influenza virus subtype H5 is reportable, destruction of birds is not always required.
Assuntos
Amazona , Vírus da Influenza A Subtipo H5N2/isolamento & purificação , Influenza Aviária/diagnóstico , Amazona/virologia , Animais , Vírus da Influenza A Subtipo H5N2/patogenicidade , Quarentena/veterinária , Reação em Cadeia da Polimerase Via Transcriptase Reversa/métodos , Reação em Cadeia da Polimerase Via Transcriptase Reversa/veterinária , Estados UnidosRESUMO
Organophosphate and carbamate pesticides inhibit acetylcholinesterase (AChE) at nerve synapses. Blood samples from 22 Hispaniolan Amazon parrots (Amazona ventralis) were assayed for cholinesterase levels by two different techniques. Using the modified Michel method, the whole-blood cholinesterase activity levels ranged from 0.082 to 0.616 deltapH/hr with a mean value of 0.35 deltapH/hr. A reference range (0.08-0.62 deltapH/hr) for cholinesterase was established in birds. The modified Ellman spectrophotometric method was used to measure AChE activity by adding acetylthiocholine or pseudocholinesterase (plasma cholinesterase) activity by adding butyrylthiocholine. The reference range of the AChE activity using the modified Ellman spectrophotometric method was 0-1.12 micromol/ml/min with a mean of 0.48 micromol/ml/min, and for pseudocholinesterase the range was 0.09-0.98 micromol/ml/min with a mean of 0.53 micromol/ml/min.
Assuntos
Acetilcolinesterase/sangue , Carbamatos , Inseticidas/intoxicação , Compostos Organofosforados , Papagaios/sangue , Acetilcolina/metabolismo , Acetilcolinesterase/efeitos dos fármacos , Animais , Valores de Referência , Espectrofotometria/veterináriaRESUMO
A 4-year old, male intact, captive-bred chinchilla (Chinchilla lanigera) was presented due to progressive exophthalmos of the right eye over a 5-month period. Ophthalmic examination revealed exophthalmos with dorsal displacement of the right globe. Retropulsion was decreased and a fluctuant, subcutaneous mass could be palpated posterior and dorsal to the central aspect of the zygomatic bone. Transdermal ultrasonography revealed a fluid-filled mass consistent with a cyst located within the ventral right orbit. Computed tomography demonstrated dorsal displacement of the globe, lateral displacement of the zygomatic arch, and numerous mineral-dense foci within the lumen of the cyst. The cyst was removed en bloc by ventral transpalpebral orbitotomy. Histopathology revealed a single capsulated cyst with multiple invaginated protoscolices, characterized by a prominent scolex with refractile hooklets, suckers, and abundant calcareous corpuscles consistent with a Taenia coenurus. Exophthalmos resolved with surgical therapy and there was no evidence of recurrence or postoperative complications over a period of 2 years. To the authors' knowledge, this is the first reported case of an orbital cyst of parasitic origin in a chinchilla.
Assuntos
Chinchila , Infecções Oculares Parasitárias/veterinária , Taenia/isolamento & purificação , Teníase/veterinária , Animais , Diagnóstico Diferencial , Exoftalmia/etiologia , Exoftalmia/veterinária , Infecções Oculares Parasitárias/complicações , Infecções Oculares Parasitárias/diagnóstico , Infecções Oculares Parasitárias/diagnóstico por imagem , Masculino , Taenia/ultraestrutura , Teníase/complicações , Teníase/diagnóstico , Teníase/diagnóstico por imagem , Tomografia Computadorizada por Raios X/veterinária , UltrassonografiaRESUMO
A skin lesion classified as a vascular malformation is reported in a young-adult, female guinea pig. The physical examination revealed a 3 x 2-cm irregularly shaped violaceous plaque located on the left caudal flank. The surface of the plaque was ulcerated and bled intermittently, resulting in fatal blood loss. On histology the mass consisted of variably sized vascular spaces filled with red blood cells and variable amounts of extramedullary haematopoietic cells, lined by well-differentiated endothelial cells often surrounded by one layer of spindle-shaped cells. Based on immunohistochemistry, the spindle cell population was confirmed to be smooth muscle cells and no proliferation of endothelial cells was found with the Ki67 proliferation marker. Histological and immunohistochemical findings were consistent with a vascular malformation. Classification of vascular malformations and potential treatments are discussed. To the authors' knowledge, this is the first reported case of a cutaneous vascular lesion in a guinea pig.