Detalhe da pesquisa
1.
Digitoxigenin presents an effective and selective antileishmanial action against Leishmania infantum and is a potential therapeutic agent for visceral leishmaniasis.
Parasitol Res
; 120(1): 321-335, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33191446
2.
Inhibition of the sphingosine-1-phosphate pathway promotes the resolution of neutrophilic inflammation.
Eur J Immunol
; 49(7): 1038-1051, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30939218
3.
Synthesis and cytotoxicity evaluation of glycosidic derivatives of lawsone against breast cancer cell lines.
Bioorg Med Chem Lett
; 30(2): 126817, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31810778
4.
(3,3â³)-Linked Biflavanones from Ouratea spectabilis and Their Effects on the Release of Proinflammatory Cytokines in THP-1 Cells.
J Nat Prod
; 83(6): 1891-1898, 2020 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32484349
5.
The Cyclitol L-(+)-Bornesitol as an Active Marker for the Cardiovascular Activity of the Brazilian Medicinal Plant Hancornia speciosa.
Biol Pharm Bull
; 42(12): 2076-2082, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31787722
6.
Cytotoxic effects of the cardenolide convallatoxin and its Na,K-ATPase regulation.
Mol Cell Biochem
; 428(1-2): 23-39, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28176244
7.
Oral sub-chronic treatment with Terminalia phaeocarpa Eichler (Combretaceae) reduces liver PTP1B activity in a murine model of diabetes.
J Ethnopharmacol
; 306: 116164, 2023 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36681165
8.
Bioguided chemical characterization of pequi (Caryocar brasiliense) fruit peels towards an anti-diabetic activity.
Food Chem
; 345: 128734, 2021 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33310563
9.
In vitro and in vivo antileishmanial activity of ß-acetyl-digitoxin, a cardenolide of Digitalis lanata potentially useful to treat visceral leishmaniasis.
Parasite
; 28: 38, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851916
10.
Determination of l-(+)-bornesitol, the hypotensive constituent of Hancornia speciosa, in rat plasma by LC-MS/MS and its application on a pharmacokinetic study.
Biomed Pharmacother
; 132: 110900, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33113433
11.
New 99mTc-Labeled Digitoxigenin Derivative for Cancer Cell Identification.
ACS Omega
; 4(26): 22048-22056, 2019 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31891085
12.
Purification and characterization of malonyl-coenzyme A: 21-hydroxypregnane 21-O-malonyltransferase (Dp21MaT) from leaves of Digitalis purpurea L.
Phytochemistry
; 69(3): 619-26, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17945319
13.
A simple chemical method for synthesizing malonyl hemiesters of 21-hydroxypregnanes, potential intermediates in cardenolide biosynthesis.
Steroids
; 73(4): 458-65, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18249427
14.
Cytotoxic and cytostatic effects of digitoxigenin monodigitoxoside (DGX) in human lung cancer cells and its link to Na,K-ATPase.
Biomed Pharmacother
; 97: 684-696, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29101813
15.
Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death.
Front Pharmacol
; 9: 70, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29545747
16.
Synthesis of a putative substrate for malonyl-coenzyme A: 21-hydroxypregnane 21-O-malonyltransferase and development of an HPLC method for the quantification of the enzyme reaction.
J Chromatogr B Analyt Technol Biomed Life Sci
; 860(2): 195-201, 2007 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18232079
17.
Inhibition of cell proliferation, invasion and migration by the cardenolides digitoxigenin monodigitoxoside and convallatoxin in human lung cancer cell line.
Nat Prod Res
; 30(11): 1327-31, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26252521
18.
In Vitro TNF-α Inhibitory Activity of Brazilian Plants and Anti-Inflammatory Effect of Stryphnodendron adstringens in an Acute Arthritis Model.
Evid Based Complement Alternat Med
; 2016: 9872598, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27867403