Detalhe da pesquisa
1.
Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro.
Drug Metab Dispos
; 51(3): 293-305, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36446607
2.
Involvement of Pazopanib and Sunitinib Aldehyde Reactive Metabolites in Toxicity and Drug-Drug Interactions in Vitro and in Patient Samples.
Chem Res Toxicol
; 33(1): 181-190, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31535851
3.
Identifying the reactive metabolites of tyrosine kinase inhibitors in a comprehensive approach: Implications for drug-drug interactions and hepatotoxicity.
Med Res Rev
; 39(6): 2105-2152, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31111528
4.
Pharmacodynamic Therapeutic Drug Monitoring for Cancer: Challenges, Advances, and Future Opportunities.
Ther Drug Monit
; 41(2): 142-159, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30883508
5.
Safety of oral hydration after cisplatin infusion in an outpatient lung cancer unit.
Support Care Cancer
; 27(5): 1679-1686, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30120556
6.
Determination of unbound fraction of pazopanib in vitro and in cancer patients reveals albumin as the main binding site.
Invest New Drugs
; 34(1): 41-8, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26572909
7.
Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes - detailed studies on CYP3A inhibitors.
Eur J Pharm Sci
; 198: 106735, 2024 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38423227
8.
Is spontaneous reporting always the most important information supporting drug withdrawals for pharmacovigilance reasons in France?
Pharmacoepidemiol Drug Saf
; 21(12): 1289-94, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22961933
9.
An automated cocktail method for in vitro assessment of direct and time-dependent inhibition of nine major cytochrome P450 enzymes - application to establishing CYP2C8 inhibitor selectivity.
Eur J Pharm Sci
; 162: 105810, 2021 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33753217
10.
VOTRAGE study: Phase I dose-escalation study of pazopanib in unfit older patients.
J Geriatr Oncol
; 12(5): 759-764, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33715996
11.
Formulae recently proposed to estimate renal glomerular filtration rate improve the prediction of carboplatin clearance.
Cancer Chemother Pharmacol
; 85(3): 585-592, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31915969
12.
Clinical Pharmacokinetics and Pharmacodynamics of Dabrafenib.
Clin Pharmacokinet
; 58(4): 451-467, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30094711
13.
Simultaneous monitoring of pazopanib and its metabolites by UPLC-MS/MS.
J Pharm Biomed Anal
; 154: 373-383, 2018 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29571135
14.
Metalloporphyrin-Catalyzed Oxidation of Sunitinib and Pazopanib, Two Anticancer Tyrosine Kinase Inhibitors: Evidence for New Potentially Toxic Metabolites.
J Med Chem
; 61(17): 7849-7860, 2018 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30102538
15.
[5-fluorouracil therapeutic drug monitoring: Update and recommendations of the STP-PT group of the SFPT and the GPCO-Unicancer]. / Suivi thérapeutique pharmacologique du 5-fluorouracile : mise au point et recommandations du groupe STP-PT de la SFPT et du GPCO-Unicancer.
Bull Cancer
; 105(9): 790-803, 2018 Sep.
Artigo
em Francês
| MEDLINE | ID: mdl-30103904
16.
Correction to: Formulae recently proposed to estimate renal glomerular filtration rate improve the prediction of carboplatin clearance.
Cancer Chemother Pharmacol
; 88(1): 171, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33847805