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Aim This research aimed to assess and compare the postoperative sensitivity in class V cavity when restored with Cention-N and resin-modified glass ionomer cement (RMGIC). This study used the Schiff scale to assess sensitivity in the class V cavity. Materials and methods This was an in vivo study performed in the Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College and Hospital, Sawangi Meghe, Maharashtra. Patients included in this study were randomly selected from regular outpatient departments diagnosed with class V cavities and referred for restorative treatment. These patients were segregated into Group A and Group B. Demographic information, detailed history of any medical condition, dental history, any allergy related to resins, and another group of drugs were recorded. The in vivo study involved 36 patients, 18 in each group, who presented at Sharad Pawar Dental College and Hospital. Inform consent was taken from all patients. The subjects' responses were evaluated using a Schiff analog scale to assess postoperative sensitivity to an air blast stimulus. Results The study included all 36 patients aged between 18 and 40 years. All 36 patients were segregated into two distinct groups. Two groups of 18 patients in each group were restored with Cention-N and RMGIC in groups A and B, respectively. It was determined that RMGIC exhibits a relatively higher incidence of postoperative sensitivity than Cention-N. It was determined that the difference was statistically relevant. Conclusion Considering the limitations of this study, it can be concluded that RMGIC shows more postoperative sensitivity than other groups on the first, second, and seventh days. Thus, it is concluded that Cention-N can be a superior alternative to RMGIC.
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BACKGROUND: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has significant health implications. Anemia is usually an unseen comorbidity, which could significantly affect outcomes in AECOPD patients, and there is limited data to support this. We conducted this study to assess the effect of anemia on this patient population. METHODS: We performed a retrospective cohort study using the National (Nationwide) Inpatient Sample (NIS) data from 2008 to 2014. Patients with AECOPD and anemia with age >40 years were identified using appropriate International Classification of Diseases, Ninth Revision (ICD-9) codes, excluding transfer out to other hospitals. We calculated the Charlson Comorbidity Index as a measure of associated comorbidities. We analyzed bivariate group comparisons in patients with and without anemia. Odds ratios were calculated using multivariate logistic and linear regression analysis using SAS version 9.4 (2013; SAS Institute Inc. Cary, North Carolina, United States). RESULTS: Among 3,331,305 patients hospitalized with AECOPD, 567,982 (17.0%) had anemia as a comorbidity. The majority of patients were elderly, women, and white. After adjusting for potential confounders in regression, mortality (adjusted OR (aOR) 1.25, 95%CI: 1.18-1.32), length of hospital stay (ß 0.79, 95%Cl 0.76-0.82), and hospitalization cost (ß 6873, 95%Cl 6437-7308) were significantly higher in patients with anemia. In addition, patients with anemia required significantly higher blood transfusion (aOR 16.9, 95%CI 16.1-17.8), invasive ventilator support (aOR 1.72, 95%CI 1.64-1.79), and non-invasive ventilator support (aOR 1.21, 95%CI 1.17-1.26). CONCLUSION: In this first retrospective largest cohort study on this topic, we find anemia is a significant comorbidity associated with adverse outcomes and healthcare burden in hospitalized AECOPD patients. We should focus on close monitoring and management of anemia to improve the outcomes in this population.
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Most of the currently used medications for the treatment of oral ulcers focus primarily on providing symptomatic relief and preventing secondary infections. Not much attention has been paid in the past on agents that can promote healing of these lesions. In the current study, we have tested and compared the efficacy of such wound healing promoting agents i.e. Propolis (product obtained from Bees) and a newly developed herbal ointment (containing extracts of Azadirachta indica (Neem), Linum usitatissimum L.(Linseed) oil, and resin of Shorea robusta) in experimental rabbits. METHODOLOGY: Traumatic oral ulcers were inflicted in experimental rabbits (New Zealand white) with the help of a punch biopsy instrument. The animals were then divided into three groups each group consisted of 12 animals (n = 12), Group I was the untreated control group and Group II was topically treated with nonalcohol extract of propolis and Group III was treated with newly developed herbal ointment. Histological healing scores of the ulcers were evaluated on day 7 and day 14. Data were statistically analyzed using descriptive and inferential statistic methods. RESULTS: In Group III treated with newly developed herbal ointment, significantly higher healing scores, in comparison to the untreated control group (Group I) and propolis (Group II) was observed on day 7 and 14. Improved healing scores in prapolis-treated group were observed than the untreated control group. However, the difference was not statistically significant on both day 7 and day 14. CONCLUSION: With the newly developed herbal ointment, superior healing of traumatic oral ulcers was observed.