Detalhe da pesquisa
1.
HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα.
Mol Cell
; 55(1): 31-46, 2014 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24882211
2.
Efficient consideration of coordinated water molecules improves computational protein-protein and protein-ligand docking discrimination.
PLoS Comput Biol
; 16(9): e1008103, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32956350
3.
Synthesis of apo-13- and apo-15-lycopenoids, cleavage products of lycopene that are retinoic acid antagonists.
J Lipid Res
; 58(5): 1021-1029, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28250025
4.
Ca2+/calmodulin-dependent protein kinase II-based regulation of voltage-gated Na+ channel in cardiac disease.
Circulation
; 126(17): 2084-94, 2012 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23008441
5.
Discovery of benzamide analogs as negative allosteric modulators of human neuronal nicotinic receptors: pharmacophore modeling and structure-activity relationship studies.
Bioorg Med Chem
; 21(15): 4730-43, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23757208
6.
Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities.
J Nat Prod
; 76(2): 243-9, 2013 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23327794
7.
Autocatalytic cleavage of human gamma-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95.
J Biol Chem
; 286(33): 28876-28888, 2011 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21712391
8.
Negative allosteric modulators that target human alpha4beta2 neuronal nicotinic receptors.
J Pharmacol Exp Ther
; 334(3): 761-74, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20551292
9.
Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery.
J Pharmacol Exp Ther
; 328(2): 504-15, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18984653
10.
Modulation of DNA methylation by a sesquiterpene lactone parthenolide.
J Pharmacol Exp Ther
; 329(2): 505-14, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19201992
11.
Curcumin is a potent DNA hypomethylation agent.
Bioorg Med Chem Lett
; 19(3): 706-9, 2009 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19112019
12.
Conformational changes in the lower palm domain of ASIC1a contribute to desensitization and RFamide modulation.
PLoS One
; 8(8): e71733, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23977127
13.
ZIP8 regulates host defense through zinc-mediated inhibition of NF-κB.
Cell Rep
; 3(2): 386-400, 2013 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23403290
14.
Defining the putative inhibitory site for a selective negative allosteric modulator of human α4ß2 neuronal nicotinic receptors.
ACS Chem Neurosci
; 3(9): 682-92, 2012 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23019495
15.
Identification of a negative allosteric site on human α4ß2 and α3ß4 neuronal nicotinic acetylcholine receptors.
PLoS One
; 6(9): e24949, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21949802
16.
Discovery of Novel α4ß2 Neuronal Nicotinic Receptor Modulators through Structure-Based Virtual Screening.
ACS Med Chem Lett
; 2(11): 855-60, 2011 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24936233
17.
Structure-activity relationship studies of sulfonylpiperazine analogues as novel negative allosteric modulators of human neuronal nicotinic receptors.
J Med Chem
; 54(24): 8681-92, 2011 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22060139