Detalhe da pesquisa
1.
Zebrafish as a Mainstream Model for In Vivo Systems Pharmacology and Toxicology.
Annu Rev Pharmacol Toxicol
; 63: 43-64, 2023 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36151053
2.
An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency.
PLoS Genet
; 18(6): e1010228, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35653343
3.
Corticosteroid sensitization drives opioid addiction.
Mol Psychiatry
; 27(5): 2492-2501, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35296810
4.
Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish.
FASEB J
; 34(1): 1546-1557, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914600
5.
Emerimicins V-X, 15-Residue Peptaibols Discovered from an Acremonium sp. through Integrated Genomic and Chemical Approaches.
J Nat Prod
; 84(4): 1113-1126, 2021 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33617244
6.
Discovery of a Potent Conorfamide from Conus episcopatus Using a Novel Zebrafish Larvae Assay.
J Nat Prod
; 84(4): 1232-1243, 2021 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33764053
7.
Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
Nature
; 523(7561): 481-5, 2015 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26098369
8.
TRPswitch-A Step-Function Chemo-optogenetic Ligand for the Vertebrate TRPA1 Channel.
J Am Chem Soc
; 142(41): 17457-17468, 2020 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32966062
9.
Cyp1 Inhibition Prevents Doxorubicin-Induced Cardiomyopathy in a Zebrafish Heart-Failure Model.
Chembiochem
; 21(13): 1905-1910, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32003101
10.
Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells.
Nat Chem Biol
; 14(9): 844-852, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29988067
11.
Use of Zebrafish in Drug Discovery Toxicology.
Chem Res Toxicol
; 33(1): 95-118, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31625720
12.
Boholamide A, an APD-Class, Hypoxia-Selective Cyclodepsipeptide.
J Nat Prod
; 83(4): 1249-1257, 2020 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32186874
13.
Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with Isonitriles.
Angew Chem Int Ed Engl
; 58(27): 9043-9048, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31062496
14.
Bioorthogonal Removal of 3-Isocyanopropyl Groups Enables the Controlled Release of Fluorophores and Drugs in Vivo.
J Am Chem Soc
; 140(27): 8410-8414, 2018 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29927585
15.
σ1 receptor ligands control a switch between passive and active threat responses.
Nat Chem Biol
; 12(7): 552-8, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27239788
16.
Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds.
Nat Chem Biol
; 12(7): 559-66, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27239787
17.
Bonnevillamides, Linear Heptapeptides Isolated from a Great Salt Lake-Derived Streptomyces sp.
Mar Drugs
; 15(7)2017 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28672784
18.
The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6.
Blood
; 123(14): 2261-8, 2014 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24501215
19.
Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions.
Proc Natl Acad Sci U S A
; 110(8): E776-85, 2013 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382188
20.
Systematic approaches to toxicology in the zebrafish.
Annu Rev Pharmacol Toxicol
; 52: 433-53, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22017682