Detalhe da pesquisa
1.
Towards the second generation of Boceprevir: Dithianes as an alternative P2 substituent for 2,2-dimethyl cycloproyl proline in HCV NS3 protease inhibitors.
Bioorg Med Chem Lett
; 20(5): 1689-92, 2010 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20149655
2.
Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication.
J Med Chem
; 49(9): 2750-7, 2006 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-16640336
3.
Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor: a potential therapeutic agent for the treatment of hepatitis C infection.
J Med Chem
; 49(20): 6074-86, 2006 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-17004721
4.
Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048 (1), and the discovery of posaconazole [Sch 56592; 2 or (S,S)-5].
Bioorg Med Chem Lett
; 16(1): 186-90, 2006 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16260134