Detalhe da pesquisa
1.
MED12 controls the response to multiple cancer drugs through regulation of TGF-ß receptor signaling.
Cell
; 151(5): 937-50, 2012 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23178117
2.
Prognostic value of blood biomarkers in steroid-refractory or steroid-dependent acute graft-versus-host disease: a REACH2 analysis.
Blood
; 141(22): 2771-2779, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36827620
3.
Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma.
Nature
; 508(7494): 118-22, 2014 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24670642
4.
A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells.
Mol Cell Proteomics
; 17(10): 1892-1908, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29970458
5.
Comparative Network Reconstruction using mixed integer programming.
Bioinformatics
; 34(17): i997-i1004, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30423075
6.
Modelling signalling networks from perturbation data.
Bioinformatics
; 34(23): 4079-4086, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29931053
7.
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.
Nature
; 483(7387): 100-3, 2012 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22281684
8.
Preclinical studies on the use of a P-selectin-blocking monoclonal antibody to halt progression of myelofibrosis in the Gata1low mouse model.
Exp Hematol
; 117: 43-61, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36191885
9.
CRISPR Screening Identifies Mechanisms of Resistance to KRASG12C and SHP2 Inhibitor Combinations in Non-Small Cell Lung Cancer.
Cancer Res
; 83(24): 4130-4141, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37934115
10.
A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors.
Nat Cancer
; 4(2): 240-256, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36759733
11.
Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models.
Comput Struct Biotechnol J
; 18: 323-331, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32099592
12.
Deciphering mechanisms of response and resistance in large-scale mouse cancer screens.
Curr Opin Genet Dev
; 54: 48-54, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30954760
13.
Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities.
Nat Cell Biol
; 21(6): 778-790, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31160710
14.
SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.
Nat Med
; 24(7): 961-967, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29808006
15.
PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs.
Cell Rep
; 12(12): 1978-85, 2015 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26365186
16.
Intrinsic resistance to MEK inhibition in KRAS mutant lung and colon cancer through transcriptional induction of ERBB3.
Cell Rep
; 7(1): 86-93, 2014 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24685132