Detalhe da pesquisa
1.
Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism.
Mol Cancer Res
; 7(5): 745-754, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19435822
2.
Constitutive activation of AKT pathway inhibits TNF-induced apoptosis in mitochondrial DNA-deficient human myelogenous leukemia ML-1a.
Cancer Lett
; 268(1): 31-7, 2008 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18468786
3.
Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells.
Cancer Res
; 65(20): 9164-8, 2005 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16230374
4.
Hypothesis generation in signaling networks.
J Comput Biol
; 13(9): 1546-57, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17147477
5.
The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells.
Oncogene
; 23(53): 8571-80, 2004 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-15467756
6.
Resistance of human ovarian cancer cells to tumor necrosis factor alpha is a consequence of nuclear factor kappaB-mediated induction of Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory protein.
Endocrinology
; 144(2): 623-30, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12538625
7.
BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation.
Sci Signal
; 6(257): ra2, 2013 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23300339
8.
Tocotrienols inhibit AKT and ERK activation and suppress pancreatic cancer cell proliferation by suppressing the ErbB2 pathway.
Free Radic Biol Med
; 51(6): 1164-74, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21723941
9.
Establishment of three-dimensional cultures of human pancreatic duct epithelial cells.
Biochem Biophys Res Commun
; 358(3): 698-703, 2007 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-17512909
10.
PTEN down regulates AP-1 and targets c-fos in human glioma cells via PI3-kinase/Akt pathway.
Mol Cell Biochem
; 300(1-2): 77-87, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17235455
11.
The IL-1 receptor accessory protein is essential for PI 3-kinase recruitment and activation.
Biochem Biophys Res Commun
; 316(4): 1022-8, 2004 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-15044087