Detalhe da pesquisa
1.
The protean prion protein.
PLoS Biol
; 18(6): e3000754, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32584805
2.
Full atomistic model of prion structure and conversion.
PLoS Pathog
; 15(7): e1007864, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31295325
3.
Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies.
PLoS Pathog
; 15(10): e1008117, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31644574
4.
All-atom simulation of the HET-s prion replication.
PLoS Comput Biol
; 16(9): e1007922, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32946455
5.
Determining the Relative Susceptibility of Four Prion Protein Genotypes to Atypical Scrapie.
Anal Chem
; 90(2): 1255-1262, 2018 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29240410
6.
The Structural Architecture of an Infectious Mammalian Prion Using Electron Cryomicroscopy.
PLoS Pathog
; 12(9): e1005835, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27606840
7.
Cofactors influence the biological properties of infectious recombinant prions.
Acta Neuropathol
; 135(2): 179-199, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29094186
8.
Proteomic Studies Reveal Disrupted in Schizophrenia 1 as a Player in Both Neurodevelopment and Synaptic Function.
Int J Mol Sci
; 20(1)2018 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30597994
9.
Quantitating PrP Polymorphisms Present in Prions from Heterozygous Scrapie-Infected Sheep.
Anal Chem
; 89(1): 854-861, 2017 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27936597
10.
Neuropeptide precursor VGF is genetically associated with social anhedonia and underrepresented in the brain of major mental illness: its downregulation by DISC1.
Hum Mol Genet
; 23(22): 5859-65, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24934694
11.
DISC1 regulates expression of the neurotrophin VGF through the PI3K/AKT/CREB pathway.
J Neurochem
; 135(3): 598-605, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26212236
12.
Larger aggregates of mutant seipin in Celia's Encephalopathy, a new protein misfolding neurodegenerative disease.
Neurobiol Dis
; 83: 44-53, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26282322
13.
Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits.
Hum Mol Genet
; 21(20): 4406-18, 2012 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22798627
14.
Elucidating the structure of an infectious protein.
PLoS Pathog
; 13(4): e1006229, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28406976
15.
PK-sensitive PrP is infectious and shares basic structural features with PK-resistant PrP.
PLoS Pathog
; 8(3): e1002547, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22396643
16.
A new seipin-associated neurodegenerative syndrome.
J Med Genet
; 50(6): 401-9, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23564749
17.
Oxidation of methionine 216 in sheep and elk prion protein is highly dependent upon the amino acid at position 218 but is not important for prion propagation.
Biochemistry
; 52(12): 2139-47, 2013 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23458153
18.
A Mass Spectrometry-Based Method of Quantifying the Contribution of the Lysine Polymorphism at Position 171 in Sheep PrP.
J Am Soc Mass Spectrom
; 34(2): 245-254, 2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36622794
19.
A tetracationic porphyrin with dual anti-prion activity.
iScience
; 26(9): 107480, 2023 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37636075
20.
Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation.
Acta Neuropathol Commun
; 11(1): 145, 2023 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679832