Detalhe da pesquisa
1.
Conditional Dependency of LP-184 on Prostaglandin Reductase 1 is Synthetic Lethal in Pancreatic Cancers with DNA Damage Repair Deficiencies.
Mol Cancer Ther
; 22(10): 1182-1190, 2023 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37552607
2.
Trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer growth and immune suppression via phospholipid scramblase anoctamin 6 (ANO6).
bioRxiv
; 2023 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37745612
3.
Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression.
Cancer Discov
; 11(2): 446-479, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33127842
4.
Cholesterol Pathway Inhibition Induces TGF-ß Signaling to Promote Basal Differentiation in Pancreatic Cancer.
Cancer Cell
; 38(4): 567-583.e11, 2020 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32976774
5.
Targeted delivery of chemotherapy using HSP90 inhibitor drug conjugates is highly active against pancreatic cancer models.
Oncotarget
; 8(3): 4399-4409, 2017 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27779106
6.
Screening of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3-MYC Interactions as a Target in Pancreatic Cancer.
Clin Cancer Res
; 22(24): 6153-6163, 2016 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27384421
7.
Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR.
Cell Rep
; 12(11): 1927-38, 2015 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26344763
8.
Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.
Cancer Discov
; 3(1): 96-111, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23125191