Detalhe da pesquisa
1.
Plasma proteomic associations with genetics and health in the UK Biobank.
Nature
; 622(7982): 329-338, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37794186
2.
Evaluating and implementing block jackknife resampling Mendelian randomization to mitigate bias induced by overlapping samples.
Hum Mol Genet
; 32(2): 192-203, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35932451
3.
Harnessing tissue-specific genetic variation to dissect putative causal pathways between body mass index and cardiometabolic phenotypes.
Am J Hum Genet
; 109(2): 240-252, 2022 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35090585
4.
Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.
PLoS Biol
; 20(2): e3001547, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35213538
5.
A lifecourse mendelian randomization study highlights the long-term influence of childhood body size on later life heart structure.
PLoS Biol
; 20(6): e3001656, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35679339
6.
Estimation of causal effects of a time-varying exposure at multiple time points through multivariable mendelian randomization.
PLoS Genet
; 18(7): e1010290, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35849575
7.
Integrative multiomics analysis highlights immune-cell regulatory mechanisms and shared genetic architecture for 14 immune-associated diseases and cancer outcomes.
Am J Hum Genet
; 108(12): 2259-2270, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34741802
8.
Ultra-processed foods, adiposity and risk of head and neck cancer and oesophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study: a mediation analysis.
Eur J Nutr
; 63(2): 377-396, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37989797
9.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
PLoS Genet
; 17(1): e1009224, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33417599
10.
Childhood adiposity and novel subtypes of adult-onset diabetes: a Mendelian randomisation and genome-wide genetic correlation study.
Diabetologia
; 66(6): 1052-1056, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36843089
11.
Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood.
Diabetologia
; 66(8): 1472-1480, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37280435
12.
Association between genetically proxied PCSK9 inhibition and prostate cancer risk: A Mendelian randomisation study.
PLoS Med
; 20(1): e1003988, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36595504
13.
Multi-omics analyses of cognitive traits and psychiatric disorders highlights brain-dependent mechanisms.
Hum Mol Genet
; 2021 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33481009
14.
Separating the genetics of childhood and adult obesity: a validation study of genetic scores for body mass index in adolescence and adulthood in the HUNT Study.
Hum Mol Genet
; 29(24): 3966-3973, 2021 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33276378
15.
Disentangling the aetiological pathways between body mass index and site-specific cancer risk using tissue-partitioned Mendelian randomisation.
Br J Cancer
; 128(4): 618-625, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36434155
16.
Characterizing the Causal Pathway for Genetic Variants Associated with Neurological Phenotypes Using Human Brain-Derived Proteome Data.
Am J Hum Genet
; 106(6): 885-892, 2020 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32413284
17.
Smoking, DNA Methylation, and Lung Function: a Mendelian Randomization Analysis to Investigate Causal Pathways.
Am J Hum Genet
; 106(3): 315-326, 2020 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32084330
18.
Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study.
BMC Med
; 21(1): 5, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36600297
19.
Harnessing Whole Genome Polygenic Risk Scores to Stratify Individuals Based on Cardiometabolic Risk Factors and Biomarkers at Age 10 in the Lifecourse-Brief Report.
Arterioscler Thromb Vasc Biol
; 42(3): 362-365, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35045726
20.
Leveraging family history data to disentangle time-varying effects on disease risk using lifecourse mendelian randomization.
Eur J Epidemiol
; 38(7): 765-769, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156976