[Collagen-induced platelet aggregation in K562 neoplastic cells culture media]. / L'aggregazione piastrinica indotta da collagene in presenza di terreno di coltura di cellule neoplastiche K562.

The evidence suggests that the propagation of neoplastic cells by solid tumors, seem the platelets have a protective role on the neoplastic cells respect to immunocompetent system. In this study, the AA. valued the variation of platelet aggregation induced by collagen when PRP was incubated with liquid culture of neoplastic cells K562. The preliminary results, show the platelet aggregation induced by collagen, increase alter interaction with this liquid culture.

[Platelet aggregation induced by adenosine diphosphate, collagen and adrenaline in human platelet subpopulations]. / Aggregazione piastrinica indotta da adenosin difosfato, collagene ed adrenalina nelle sottopopolazioni piastriniche umane.

The study of platelet aggregation is normally carried out with the use of "Platelet Rich Plasma" (PRP) in which is grouped the overall platelets population. We have divided this population in three defined subclasses by gradients with discontinuous density, so as to test their own functional response towards three aggregant agents: adenosine diphosphate, epinephrine and collagen. The obtained results have been compared by an Aggregation Index, calculated as a ratio between the maximum percentage of aggregation and platelets mass. In this way it is pointed out a discriminating behaviour in three groups of thrombocytes relative to a functional different attitude towards different inducers and associated to an activation of heterogeneous way.

[Effects of aminoglycosides on T and B lymphocyte populations: in vitro study]. / Effetti degli aminoglicosidi sulle popolazioni linfocitarie T e B: studio "in vitro".

The authors tested the influence of gentamycin, spectinomycin,and dihydrostreptomycin on the formation of EAChu and EAT rosettes and they have found a significant reduction of the percentage of EAChu rosettes. Probably this reduction is due to an interaction with the receptor sites for the Complement of B lymphocytes and/or an in vitro denaturation Complement.