Detalhe da pesquisa
1.
Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition.
PLoS Pathog
; 17(7): e1009734, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34310651
2.
IL-17 can be protective or deleterious in murine pneumococcal pneumonia.
PLoS Pathog
; 14(5): e1007099, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29813133
3.
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections.
Science
; 380(6652): 1349-1356, 2023 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37384702
4.
Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response.
PLoS Negl Trop Dis
; 16(9): e0010779, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36170238
5.
Discovery of Novel Quinoline-Based Proteasome Inhibitors for Human African Trypanosomiasis (HAT).
J Med Chem
; 65(17): 11776-11787, 2022 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993839
6.
Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice.
Nat Commun
; 12(1): 1052, 2021 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33594070
7.
In Vivo Bioluminescence Imaging to Assess Compound Efficacy Against Trypanosoma brucei.
Methods Mol Biol
; 2116: 801-817, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32221957
8.
Anti-Trypanosomal Proteasome Inhibitors Cure Hemolymphatic and Meningoencephalic Murine Infection Models of African Trypanosomiasis.
Trop Med Infect Dis
; 5(1)2020 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32079320
9.
Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors.
Nat Microbiol
; 5(10): 1207-1216, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32661312
10.
Expression of the lux genes in Streptococcus pneumoniae modulates pilus expression and virulence.
PLoS One
; 13(1): e0189426, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29342160
11.
RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse.
Sci Rep
; 7(1): 6156, 2017 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28733613
12.
Attempts to Image the Early Inflammatory Response during Infection with the Lymphatic Filarial Nematode Brugia pahangi in a Mouse Model.
PLoS One
; 11(12): e0168602, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27992545
13.
Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes.
PLoS Negl Trop Dis
; 9(4): e0003714, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25881126
14.
In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis.
PLoS Negl Trop Dis
; 7(8): e2384, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23991236