Detalhe da pesquisa
1.
A Red Carpet for Iron Metabolism.
Cell
; 168(3): 344-361, 2017 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28129536
2.
Reactivation of developmentally silenced globin genes by forced chromatin looping.
Cell
; 158(4): 849-860, 2014 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25126789
3.
Combination of a TGF-ß ligand trap (RAP-GRL) and TMPRSS6-ASO is superior for correcting ß-thalassemia.
Am J Hematol
; 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38659383
4.
Iron restriction in sickle cell disease: When less is more.
Am J Hematol
; 2024 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38400590
5.
Novel potential therapeutics to modify iron metabolism and red cell synthesis in diseases associated with defective erythropoiesis.
Haematologica
; 108(10): 2582-2593, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37345473
6.
Correcting ß-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity.
Blood
; 136(17): 1968-1979, 2020 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32556142
7.
Transferrin receptor 2 (Tfr2) genetic deletion makes transfusion-independent a murine model of transfusion-dependent ß-thalassemia.
Am J Hematol
; 97(10): 1324-1336, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36071579
8.
Lentiviral vector ALS20 yields high hemoglobin levels with low genomic integrations for treatment of beta-globinopathies.
Mol Ther
; 29(4): 1625-1638, 2021 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515514
9.
Gene therapy of hemoglobinopathies: progress and future challenges.
Hum Mol Genet
; 28(R1): R24-R30, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31322165
10.
Heparanase Level and Procoagulant Activity Are Increased in Thalassemia and Attenuated by Janus Kinase 2 Inhibition.
Am J Pathol
; 190(10): 2146-2154, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32745462
11.
Iron metabolism under conditions of ineffective erythropoiesis in ß-thalassemia.
Blood
; 133(1): 51-58, 2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30401707
12.
Lobe specificity of iron binding to transferrin modulates murine erythropoiesis and iron homeostasis.
Blood
; 134(17): 1373-1384, 2019 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31434707
13.
CYP450 Mediates Reactive Oxygen Species Production in a Mouse Model of ß-Thalassemia through an Increase in 20-HETE Activity.
Int J Mol Sci
; 22(3)2021 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33498614
14.
Carbonyl iron and iron dextran therapies cause adverse effects on bone health in juveniles with chronic kidney disease.
Kidney Int
; 98(5): 1210-1224, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32574618
15.
Hepcidin agonists as therapeutic tools.
Blood
; 131(16): 1790-1794, 2018 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29523504
16.
Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin.
Blood
; 131(8): 899-910, 2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29237594
17.
Minihepcidins improve ineffective erythropoiesis and splenomegaly in a new mouse model of adult ß-thalassemia major.
Haematologica
; 105(7): 1835-1844, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31582543
18.
Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome.
Blood
; 130(9): 1144-1155, 2017 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28729432
19.
Decreasing TfR1 expression reverses anemia and hepcidin suppression in ß-thalassemic mice.
Blood
; 129(11): 1514-1526, 2017 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28151426
20.
2'-O-methoxyethyl splice-switching oligos correct splicing from IVS2-745 ß-thalassemia patient cells restoring HbA production and chain rebalance.
Haematologica
; 106(5): 1433-1442, 2019 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32439726