Detalhe da pesquisa
1.
Integrated proteomics identifies PARP inhibitor-induced prosurvival signaling changes as potential vulnerabilities in ovarian cancer.
J Biol Chem
; 298(11): 102550, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36183837
2.
Differential Chemoproteomics Reveals MARK2/3 as Cell Migration-Relevant Targets of the ALK Inhibitor Brigatinib.
Chembiochem
; 24(11): e202200766, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36922348
3.
Turning liabilities into opportunities: Off-target based drug repurposing in cancer.
Semin Cancer Biol
; 68: 209-229, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32044472
4.
Novel Human-Derived RET Fusion NSCLC Cell Lines Have Heterogeneous Responses to RET Inhibitors and Differential Regulation of Downstream Signaling.
Mol Pharmacol
; 99(6): 435-447, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33795352
5.
Lowering Sample Requirements to Study Tyrosine Kinase Signaling Using Phosphoproteomics with the TMT Calibrator Approach.
Proteomics
; 20(24): e2000116, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32865326
6.
Functional Proteomics and Deep Network Interrogation Reveal a Complex Mechanism of Action of Midostaurin in Lung Cancer Cells.
Mol Cell Proteomics
; 17(12): 2434-2447, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30217950
7.
Polypharmacology-based ceritinib repurposing using integrated functional proteomics.
Nat Chem Biol
; 13(12): 1222-1231, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28991240
8.
Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer.
J Proteome Res
; 17(1): 63-75, 2018 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29164889
9.
APOSTL: An Interactive Galaxy Pipeline for Reproducible Analysis of Affinity Proteomics Data.
J Proteome Res
; 15(12): 4747-4754, 2016 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27680298
10.
Targeting a cell state common to triple-negative breast cancers.
Mol Syst Biol
; 11(1): 789, 2015 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25699542
11.
Evaluating kinase ATP uptake and tyrosine phosphorylation using multiplexed quantification of chemically labeled and post-translationally modified peptides.
Methods
; 81: 41-9, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25782629
12.
Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells.
Proc Natl Acad Sci U S A
; 110(30): 12414-9, 2013 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23836654
13.
Unraveling the rewired network.
Nat Chem Biol
; 14(8): 746-747, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29942077
14.
Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.
Mol Syst Biol
; 9: 705, 2013 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24189400
15.
Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.
Nat Chem Biol
; 8(11): 905-912, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23023260
16.
PTEN Lipid Phosphatase Activity Suppresses Melanoma Formation by Opposing an AKT/mTOR/FRA1 Signaling Axis.
Cancer Res
; 84(3): 388-404, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38193852
17.
Differential network analysis of ROS1 inhibitors reveals lorlatinib polypharmacology through co-targeting PYK2.
Cell Chem Biol
; 31(2): 284-297.e10, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37848034
18.
A miniaturized chemical proteomic approach for target profiling of clinical kinase inhibitors in tumor biopsies.
J Proteome Res
; 12(9): 4005-17, 2013 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23901793
19.
Bidirectional Adaptive Signaling between cancer and stromal cells: mechanisms and therapeutics.
Expert Rev Proteomics
; 15(9): 697-699, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30251554
20.
KIT-D816V-independent oncogenic signaling in neoplastic cells in systemic mastocytosis: role of Lyn and Btk activation and disruption by dasatinib and bosutinib.
Blood
; 118(7): 1885-98, 2011 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21680801