Detalhe da pesquisa
1.
Effect of Opicapone on Levodopa Pharmacokinetics in Patients with Fluctuating Parkinson's Disease.
Mov Disord
; 37(11): 2272-2283, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36054562
2.
Opicapone versus placebo in the treatment of Parkinson's disease patients with end-of-dose motor fluctuation-associated pain: rationale and design of the randomised, double-blind OCEAN (OpiCapone Effect on motor fluctuations and pAiN) trial.
BMC Neurol
; 22(1): 88, 2022 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35279112
3.
Biological and physicochemical implications of the aging process on titanium and zirconia implant material surfaces.
J Prosthet Dent
; 125(1): 165-174, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32037296
4.
Efficacy and safety of eslicarbazepine acetate as adjunctive therapy for refractory focal-onset seizures in children: A double-blind, randomized, placebo-controlled, parallel-group, multicenter, phase-III clinical trial.
Epilepsy Behav
; 105: 106962, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32151803
5.
Efficacy and safety of eslicarbazepine acetate versus controlled-release carbamazepine monotherapy in newly diagnosed epilepsy: A phase III double-blind, randomized, parallel-group, multicenter study.
Epilepsia
; 59(2): 479-491, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29369348
6.
Effect of opicapone multiple-dose regimens on levodopa pharmacokinetics.
Br J Clin Pharmacol
; 83(3): 540-553, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27763682
7.
Effect of moderate liver impairment on the pharmacokinetics of opicapone.
Eur J Clin Pharmacol
; 70(3): 279-86, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24271646
8.
Effect of opicapone and entacapone upon levodopa pharmacokinetics during three daily levodopa administrations.
Eur J Clin Pharmacol
; 70(9): 1059-71, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24925090
9.
OFF-times before, during, and after nighttime sleep periods in Parkinson's disease patients with motor fluctuations and the effects of opicapone: A post hoc analysis of diary data from BIPARK-1 and -2.
Parkinsonism Relat Disord
; 123: 106971, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38631081
10.
Opicapone to Treat Early Wearing-off in Parkinson's Disease Patients: The Korean ADOPTION Trial.
Mov Disord Clin Pract
; 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38594812
11.
Response: Comparing the dosages of lacosamide, eslicarbazepine acetate, and controlled-release carbamazepine in noninferiority epilepsy monotherapy trials: How much "fair" is "fair".
Epilepsia
; 59(4): 900-901, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29604066
12.
Steady-state plasma and cerebrospinal fluid pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine in healthy volunteers.
Epilepsia
; 54(1): 108-16, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22812691
13.
Opicapone: a short lived and very long acting novel catechol-O-methyltransferase inhibitor following multiple dose administration in healthy subjects.
Br J Clin Pharmacol
; 76(5): 763-75, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23336248
14.
Safety, Tolerability, and Pharmacokinetics of FAAH Inhibitor BIA 10-2474: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Volunteers.
Clin Pharmacol Ther
; 111(2): 391-403, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33998672
15.
Opicapone as an Add-on to Levodopa in Patients with Parkinson's Disease Without Motor Fluctuations: Rationale and Design of the Phase III, Double-Blind, Randomised, Placebo-Controlled EPSILON Trial.
Neurol Ther
; 11(3): 1409-1425, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35705887
16.
The safety/tolerability of opicapone when used early in Parkinson's disease patients with levodopa-induced motor fluctuations: A post-hoc analysis of BIPARK-I and II.
Front Neurol
; 13: 994114, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36081875
17.
Redefining the strategy for the use of COMT inhibitors in Parkinson's disease: the role of opicapone.
Expert Rev Neurother
; 21(9): 1019-1033, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34525893
18.
The Added Benefit of Opicapone When Used Early in Parkinson's Disease Patients With Levodopa-Induced Motor Fluctuations: A Post-hoc Analysis of BIPARK-I and -II.
Front Neurol
; 12: 754016, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34803891
19.
Effect of eslicarbazepine acetate and oxcarbazepine on cognition and psychomotor function in healthy volunteers.
Epilepsy Behav
; 18(4): 366-73, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20708576
20.
Correction to: Effectiveness and safety of opicapone in Parkinson's disease patients with motor fluctuations: the OPTIPARK open-label study.
Transl Neurodegener
; 9(1): 14, 2020 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32345371