Clinical Policy: Critical Issues Related to Opioids in Adult Patients Presenting to the Emergency Department.

This clinical policy from the American College of Emergency Physicians addresses key issues in opioid management in adult patients presenting to the emergency department. A writing subcommittee conducted a systematic review of the literature to derive evidence-based recommendations to answer the following clinical questions: (1) In adult patients experiencing opioid withdrawal, is emergency department-administered buprenorphine as effective for the management of opioid withdrawal compared with alternative management strategies? (2) In adult patients experiencing an acute painful condition, do the benefits of prescribing a short course of opioids on discharge from the emergency department outweigh the potential harms? (3) In adult patients with an acute exacerbation of noncancer chronic pain, do the benefits of prescribing a short course of opioids on discharge from the emergency department outweigh the potential harms? (4) In adult patients with an acute episode of pain being discharged from the emergency department, do the harms of a short concomitant course of opioids and muscle relaxants/sedative-hypnotics outweigh the benefits? Evidence was graded and recommendations were made based on the strength of the available data.

Research Pioneers in Emergency Medicine-Reflections on Their Paths to Success and Advice to Aspiring Researchers: A Qualitative Study.

STUDY OBJECTIVE: Research in basic, translational, and clinical emergency medicine has made great strides since the formalization of emergency medicine as a specialty. Our objective is to identify and analyze strategies used by emergency medicine research pioneers to inform further advancement of research in emergency medicine, particularly for aspiring researchers and those in emerging areas, using emergency medicine medical education as one example. METHODS: This was a prospective, grounded-theory, qualitative study, using a constructivist/interpretivist paradigm. Leading basic science, translational, and clinical emergency medicine researchers who completed residency before 1995 were eligible for structured interviews. Thematic coding followed an iterative process until saturation was reached. A theoretic model was developed and analyzed. RESULTS: Research pioneers valued advanced methodological training and mentorship. Barriers to funding were lack of recognition of emergency medicine as a specialty, absence of a research history, and lack of training and funding resources. Deliberate interventions to improve emergency medicine research included educational sessions at national meetings, external (to emergency medicine) mentor pairings, targeted funding by emergency medicine organizations, and involvement with funding agencies. Pioneers facilitate research excellence by serving as mentors and allocating funds or protected time to develop researchers. To advance emerging subfields of research in emergency medicine, pioneers recommend advanced methodological training that is specific to the area, deliberate mentorship, and the formation of research consortia to conduct generalizable outcomes-based studies. CONCLUSION: Research pioneers in emergency medicine cite mentorship, advanced skills obtained through fellowship or graduate degrees, deliberate collaboration with experienced researchers, support from emergency medicine organizations, and forming networks as the cornerstones of success.

Unscheduled Procedural Sedation: A Multidisciplinary Consensus Practice Guideline.

The American College of Emergency Physicians (ACEP) organized a multidisciplinary effort to create a clinical practice guideline specific to unscheduled, time-sensitive procedural sedation, which differs in important ways from scheduled, elective procedural sedation. The purpose of this guideline is to serve as a resource for practitioners who perform unscheduled procedural sedation regardless of location or patient age. This document outlines the underlying background and rationale, and issues relating to staffing, practice, and quality improvement.

Patterns in computed tomography utilization among emergency physicians in an urban, academic emergency department.

We sought to determine if CT utilization rates varied by characteristics of the physician. A chart review was performed at an urban academic emergency department (ED) to identify all the CT scans ordered and patients seen for subjects 21 years of age and older by physicians between January 2001 and December 2008. "Years of experience" was defined as years of practice after residency. Various experience cutoffs were determined a priori. Physicians were labeled "academic" if they had reduced clinical hours for academic duties and "clinical" if they were physicians without "protected time." We categorized physicians as "high users" (top quartiles) and "low users" (bottom quartiles), and compared utilization rates from 2001 to 2003 to utilization rates from 2005 to 2007. There were 280 physician-years of practice, with an average experience of 6.1 years. When comparing groups of physicians with more or less than 3, 5, 10, and 15 years of experience, there were no statistically significant differences between the number of CT scans per 1,000 visits (p = 0.85; p = 0.21; p = 0.57; p = 0.08, respectively). Comparison between clinical and academic physicians yielded no differences (clinical = 98.4, academic = 104.2, p = 0.10). Low users ordered 78 CT scans per 1,000 patient visits (95 % CI 76.6-78.5), as compared to the high users that ordered 135 CT scans per 1,000 patient visits (95 % CI 131.8-139.0). We found that all of physicians stayed within their quartiles except one. While there was substantial variation among CT utilization rates by physicians at this urban emergency department, our data shows no differences between physicians with more or less clinical experience and no change in individual utilization patterns during the study period.

Computed tomography utilization rates after the placement of a scanner in an emergency department: a single-center experience.

The convenience of a computed tomography (CT) scanner in the emergency department (ED) may impact utilization rates. Our primary aim was to determine the rate of utilization before and after the placement of an ED CT scanner. Secondary aims were to determine the rate of utilization by anatomic region and during a 5-month period when the ED scanner was unavailable. We performed an electronic chart review of our ED with an annual census of 70,000 patients. We identified all patients over the age of 21 who had a CT scan performed from January 2008 to October 2010. Predetermined data elements were extracted by trained, hypothesis-blinded abstractors. Comparisons overall and within scan subtype were performed using seasonal matching. We found a CT utilization rate of 114 per 1,000 patient visits before and 139 per 1,000 patient visits after the placement of a CT scanner in the ED (p<0.0001). Linear regression analysis found a line with a slope of ß=0.114 (95 % CI=0.107-0.121) and an R2 of 0.508. CT rates increased in the following regions: head CTs by 14 per 1,000 visits (p<0.0001); neck CTs by 3 per 1,000 visits (p<0.0001); abdomen/pelvis CTs by 4 per 1,000 visits (p=0.0015); "other" CTs by 2 per 1,000 visits (p<0.0001). Increased rates of chest and facial CTs approached significance with p values of 0.05. During the 5-month downtime, utilization remained unchanged at 141 per 1,000 visits (p=0.38). Overall CT utilization increased after the placement of a scanner in the ED. Most subtypes of scan increased. Utilization was unchanged during a period of ED scanner unavailability, suggesting that increased utilization may be difficult to reverse.

Pediatric urinary tract infection: does the evidence support aggressively pursuing the diagnosis?

The epidemiology of pediatric fever has changed considerably during the past 2 decades with the development of vaccines against the most common bacterial pathogens causing bacteremia and meningitis. The decreasing incidence of these 2 conditions among vaccinated children has led to an emphasis on urinary tract infection as a remaining source of potentially hidden infections in febrile children. Emerging literature, however, has led to questions about both the degree and nature of the danger posed by urinary tract infection in nonverbal children, whereas the aggressive pursuit of the diagnosis consumes resources and leads to patient discomfort, medical risks, and potential overdiagnosis. We review both early and emerging literature to examine the utility and efficacy of early identification and treatment of urinary tract infection in children younger than 24 months. We conclude that in well children of this age, it may be reasonable to withhold or delay testing for urinary tract infection if signs of other sources are apparent or if the fever has been present for fewer than 4 to 5 days.

Head computed tomography utilization and intracranial hemorrhage rates.

Utilization of computed tomography scans (CTs) has increased dramatically in emergency departments in the USA. This study aimed to retrospectively determine the yield of CTs among all patients that received a CT of the head from 2001 to 2007, which is adjusted for patient volume. For secondary endpoints, we examined the yield of CT of the head for the following hemorrhages: (1) intracerebral, (2) subarachnoid, (3) subdural, and (4) epidural. In 2001, 3.3 head CTs were performed per 100 patients seen. This increased by 60 % to 5.2 per 100 in 2007 (p = 0.005, R (2) = 0.82). This correlated with a nonsignificant decrease in the rate of intracranial hemorrhage found by CT from 3.6 per 100 CTs in 2001 (95 % confidence interval (CI) = 2.7-4.5) to 3.0 per 100 in 2007 (95 % CI = 2.5-3.6). There were no significant differences in "positive" rates for each subgroup of intracranial hemorrhage. Our study found that the utilization of head CTs increased dramatically, but there was a corresponding increase in the number of positive findings so that the overall yield of head CTs from 2001 to 2007 remained relatively constant.

An inexpensive and easy simulation model of ocular ultrasound that mimics normal anatomy as well as abnormal ophthalmologic conditions.

We have constructed a simple and inexpensive simulation model for the educational instruction of health care providers to detect normal and abnormal ocular conditions in the bedside emergency setting. Such a training model serves to increase the comfort level in performing ocular ultrasound examinations and can increase the accuracy of examination interpretation. Ophthalmologic examinations can be difficult in the emergency setting, and ultrasound has become a useful tool in the diagnosis of emergent ocular conditions.

Calculated decisions: Canadian C-spine rule.

A review of the uses and evidence for the Canadian C-spine rule, which can be used to clinically clear cervical spine fracture without imaging.

Calculated decisions: NEXUS criteria for c-spine imaging.

A review of the uses and evidence for the NEXUS criteria for C-spine imaging, which are used to clear patients from cervical spine fracture clinically, without imaging.

Calculated decisions: modified Rankin Scale for neurologic disability.

A review of the uses and evidence for the modified Rankin Scale, which measures the degree of disability or dependence in the daily activities of people who have suffered a stroke or other causes of neurological disability.

Calculated decisions: NIH Stroke Scale/Score (NIHSS).

A review of the uses and evidence for the National Institutes of Health Scale/Score, which is used to quantify stroke severity.

Calculated decisions: Alberta Stroke Program Early CT Score (ASPECTS).

A review of the uses and evidence for the Alberta Stroke Program Early CT Score, which determines middle cerebral artery stroke severity using available computed tomography data.

The "double eights mask brace" improves the fit and protection of a basic surgical mask amidst COVID-19 pandemic.

STUDY OBJECTIVE: The COVID-19 pandemic has resulted in widespread shortages of personal protective equipment, including N95 respirators. Although basic surgical facemasks are more commonly available, their efficacy is limited due primarily to their poor face seal. This pilot study examined the impact of a rubber band mask brace on a basic surgical mask, as determined by quantitative fit testing. METHODS: Subjects wearing a basic surgical facemask and the rubber band mask brace underwent quantitative fit testing using machinery designed to certify N95 mask fit. Subjects were tested with the brace anchored behind their ears, with a paperclip behind the head, and on the side knobs of their face shields. The primary outcome measure was whether the subject passed the quantitative fit test at or above the Occupational Safety and Health Administration (OSHA)-verified standard for N95 masks. RESULTS: Subjects (n = 11) were 54.5% female, with a median height of 70 inches (interquartile range [IQR] = 68-74), weight of 170 pounds (IQR = 145-215), and body mass index (BMI) of 24.6 (IQR = 22.2-27.2), and encompassing 5 distinct N95 mask fit types. We found that 45%, 100%, and 100% of subjects passed the quantitative fit test when the brace was anchored behind the ears, with a paperclip and on a face shield, respectively. CONCLUSION: Of the 11 subjects included in the analysis, across a range of body habitus and N95 mask fit types, all passed the quantitative fit test when the mask brace was anchored on either face shield or with a paperclip. This data suggests that although the brace does not create an N95 equivalent in terms of filtration, it would offer improved protection from airborne viruses when worn with a basic surgical mask.