Detalhe da pesquisa
1.
Phenotypic analysis of multielectrode array EEG biomarkers in developing and adult male Fmr1 KO mice.
Neurobiol Dis
; 195: 106496, 2024 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38582333
2.
Conformational plasticity of the intracellular cavity of GPCR-G-protein complexes leads to G-protein promiscuity and selectivity.
Proc Natl Acad Sci U S A
; 116(24): 11956-11965, 2019 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31138704
3.
Variable G protein determinants of GPCR coupling selectivity.
Proc Natl Acad Sci U S A
; 116(24): 12054-12059, 2019 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31142646
4.
Machine Learning for Prioritization of Thermostabilizing Mutations for G-Protein Coupled Receptors.
Biophys J
; 117(11): 2228-2239, 2019 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31703801
5.
Bitopic Inhibition of ATP and Substrate Binding in Ser/Thr Kinases through a Conserved Allosteric Mechanism.
Biochemistry
; 57(45): 6387-6390, 2018 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30339352
6.
Distinct structural mechanisms determine substrate affinity and kinase activity of protein kinase Cα.
J Biol Chem
; 292(39): 16300-16309, 2017 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28821615
7.
Structural Elements in the Gαs and Gαq C Termini That Mediate Selective G Protein-coupled Receptor (GPCR) Signaling.
J Biol Chem
; 291(34): 17929-40, 2016 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27330078
8.
How Does the Proliferating Cell Nuclear Antigen Modulate Binding Specificity to Multiple Partner Proteins?
J Chem Inf Model
; 57(12): 3011-3021, 2017 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29095607
9.
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.
Development
; 139(14): 2488-99, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22675211
10.
Anaplastic Large-Cell Lymphoma (ALCL) First Manifested as a Rapidly Progressive Acute Respiratory Failure (RF): Lymph Node Biopsy Negative Presentation Posing a Diagnostic Challenge.
Cureus
; 15(4): e37619, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37197117
11.
Pulmonary Angiosarcoma With Synchronous Invasive Aspergillosis Presenting as Diffuse Alveolar Hemorrhage and Acute Kidney Injury: A Case Report of a Previously Unreported Combination Posing a Diagnostic Challenge.
Cureus
; 15(5): e38507, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37284386
12.
Molecular determinants of ligand efficacy and potency in GPCR signaling.
Science
; 382(6677): eadh1859, 2023 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38127743
13.
Recent breakthroughs in computational structural biology harnessing the power of sequences and structures.
Curr Opin Struct Biol
; 80: 102608, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37182396
14.
Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity.
Nat Commun
; 13(1): 7428, 2022 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36460632
15.
Baclofen-associated neurophysiologic target engagement across species in fragile X syndrome.
J Neurodev Disord
; 14(1): 52, 2022 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36167501
16.
The role of HER2 and HER3 in HER2-amplified cancers beyond breast cancers.
Sci Rep
; 11(1): 9091, 2021 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33907275
17.
The PDE10A Inhibitor TAK-063 Reverses Sound-Evoked EEG Abnormalities in a Mouse Model of Fragile X Syndrome.
Neurotherapeutics
; 18(2): 1175-1187, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33594533
18.
The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
Nat Commun
; 12(1): 6468, 2021 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34753908
19.
C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains.
Nat Commun
; 9(1): 2484, 2018 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29950655
20.
The use of the peroxisome proliferator-activated receptors γ agonist rosiglitazone to treat airway hyperreactivity.
Ann Allergy Asthma Immunol
; 109(1): 75-7, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22727164