Alder-Reilly Anomaly in Hurler's Syndrome in a Neonate: A Rare Case Report.

A 22-days-old male newborn baby presented with persistence of neonatal jaundice since birth. On clinical examination he had coarse facial features, a prominent forehead, enlarged tongue, icterus, hepatosplenomegaly, skeletal deformities and bilateral inguinal hernia. On investigation the peripheral smear revealed Alder-Reilly anomaly in the neutrophils suggesting mucopolysaccharidosis. Mucopolysaccharide excretion spot test of the urine was positive; and an assay for glycosaminoglycans in the urine was also high, which confirmed the clinical diagnosis of Hurler's syndrome. We present this rare case to highlight the association of Alder-Reilly anomaly and bilateral inguinal hernia in Hurler's syndrome even in neonates.

Adult filarial worm in the tissue section of a breast lump.

Filariasis is a global health hazard. Incidence of filariasis is remarkably high in Indian sub continent. Apart from typical cases it is not common to find microfilaria and adult worm in tissue section and needle aspiration of the breast lump. Presence of microfilaria and adult worm in the breast is a rare finding. We report a case of filarial nodule in the breast of a 40 years old woman who presented with a pain less mass in the breast since last one month. It was diagnosed as fibroadenoma breast. Fine needle aspiration cytology showed mainly chronic inflammatory cells. The nodule was excised in toto and processed for histopathological examination. Histopathology confirmed the adult worm with granuloma in the breast nodule.