Detalhe da pesquisa
1.
Novel triterpenoid AECHL-1 induces apoptosis in breast cancer cells by perturbing the mitochondria-endoplasmic reticulum interactions and targeting diverse apoptotic pathways.
Biochim Biophys Acta
; 1860(6): 1056-70, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26851676
2.
AECHL-1, a novel triterpenoid, targets tumor neo-vasculature and impairs the endothelial cell cytoskeleton.
Angiogenesis
; 18(3): 283-99, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25952529
3.
TNK2/ACK1-mediated phosphorylation of ATP5F1A (ATP synthase F1 subunit alpha) selectively augments survival of prostate cancer while engendering mitochondrial vulnerability.
Autophagy
; 19(3): 1000-1025, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895804
4.
Epigenetic reprogramming of cell cycle genes by ACK1 promotes breast cancer resistance to CDK4/6 inhibitor.
Oncogene
; 42(29): 2263-2277, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37330596
5.
Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance.
Cancer Res
; 82(1): 155-168, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34740892
6.
Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting.
Sci Transl Med
; 14(649): eabg4132, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35704598
7.
AECHL-1 targets breast cancer progression via inhibition of metastasis, prevention of EMT and suppression of Cancer Stem Cell characteristics.
Sci Rep
; 6: 38045, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27974826
8.
A novel SOD mimic with a redox-modulating mn (II) complex, ML1 attenuates high glucose-induced abnormalities in intracellular Ca2+ transients and prevents cardiac cell death through restoration of mitochondrial function.
Biochem Biophys Rep
; 5: 296-304, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28955837