Detalhe da pesquisa
1.
In vivo mRNA expression of a multi-mechanistic mAb combination protects against Staphylococcus aureus infection.
Mol Ther
; 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38822525
2.
A Bispecific Monoclonal Antibody Targeting Psl and PcrV Enhances Neutrophil-Mediated Killing of Pseudomonas aeruginosa in Patients with Bronchiectasis.
Am J Respir Crit Care Med
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38754132
3.
Antivirulence Bispecific Monoclonal Antibody-Mediated Protection against Pseudomonas aeruginosa Ventilator-Associated Pneumonia in a Rabbit Model.
Antimicrob Agents Chemother
; 66(2): e0202221, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34902264
4.
Performance of the Cepheid Methicillin-Resistant Staphylococcus aureus/S. aureus Skin and Soft Tissue Infection PCR Assay on Respiratory Samples from Mechanically Ventilated Patients for S. aureus Screening during the Phase 2 Double-Blind SAATELLITE Study.
J Clin Microbiol
; 60(7): e0034722, 2022 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35758652
5.
Multimechanistic Monoclonal Antibody Combination Targeting Key Staphylococcus aureus Virulence Determinants in a Rabbit Model of Prosthetic Joint Infection.
Antimicrob Agents Chemother
; 65(7): e0183220, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33903108
6.
Protective Efficacy of Monoclonal Antibodies Neutralizing Alpha-Hemolysin and Bicomponent Leukocidins in a Rabbit Model of Staphylococcus aureus Necrotizing Pneumonia.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31844012
7.
Antibacterial Monoclonal Antibodies Do Not Disrupt the Intestinal Microbiome or Its Function.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152087
8.
Microbial burden and viral exacerbations in a longitudinal multicenter COPD cohort.
Respir Res
; 21(1): 77, 2020 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32228581
9.
Mouse model of hematogenous implant-related Staphylococcus aureus biofilm infection reveals therapeutic targets.
Proc Natl Acad Sci U S A
; 114(26): E5094-E5102, 2017 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607050
10.
Efficacy of a Multimechanistic Monoclonal Antibody Combination against Staphylococcus aureus Surgical Site Infections in Mice.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31138566
11.
Treatment Efficacy of MEDI3902 in Pseudomonas aeruginosa Bloodstream Infection and Acute Pneumonia Rabbit Models.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31160288
12.
The Neutrophilic Response to Pseudomonas Damages the Airway Barrier, Promoting Infection by Klebsiella pneumoniae.
Am J Respir Cell Mol Biol
; 59(6): 745-756, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30109945
13.
Prevalence of IgG and Neutralizing Antibodies against Staphylococcus aureus Alpha-Toxin in Healthy Human Subjects and Diverse Patient Populations.
Infect Immun
; 86(3)2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29263109
14.
MEDI3902 Correlates of Protection against Severe Pseudomonas aeruginosa Pneumonia in a Rabbit Acute Pneumonia Model.
Antimicrob Agents Chemother
; 62(5)2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29483116
15.
Neutralizing Alpha-Toxin Accelerates Healing of Staphylococcus aureus-Infected Wounds in Nondiabetic and Diabetic Mice.
Antimicrob Agents Chemother
; 62(3)2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311091
16.
Moving toward endotypes in atopic dermatitis: Identification of patient clusters based on serum biomarker analysis.
J Allergy Clin Immunol
; 140(3): 730-737, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28412391
17.
Effects of Tedizolid Phosphate on Survival Outcomes and Suppression of Production of Staphylococcal Toxins in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28137816
18.
Targeting Alpha Toxin To Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28115346
19.
Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893.
Antimicrob Agents Chemother
; 60(9): 5312-21, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27324766
20.
Critical Role of Alpha-Toxin and Protective Effects of Its Neutralization by a Human Antibody in Acute Bacterial Skin and Skin Structure Infections.
Antimicrob Agents Chemother
; 60(10): 5640-8, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27401576