Co-occurrence of Guillain-Barre syndrome and rheumatoid arthritis in a young female: A case report from a low middle-income country.

Key Clinical Message: We present the case of an adult female who had rheumatoid arthritis at first but later tested positive for Guillain-Barré syndrome (GBS). In symptomatic GBS patients (related to large joints), physicians (and therapists) should consider rheumatoid arthritis when risk factors are present. Abstract: The co-existence of GBS and other autoimmune disorders is uncommon. We present the case of an adult female who had rheumatoid arthritis at first but later tested positive for GBS. Further details are provided regarding the interdisciplinary diagnostic and therapy strategy that led to the patient's complete recovery. An adult female patient with rheumatoid arthritis presented with progressive weakness in her lower limbs, affecting her arm and causing numbness in her left hand and bilateral lower limbs. She has not passed stool for the last 2 days and has experienced gastroenteritis with watery, profuse diarrhea. On admission, the patient was awake, alert, and able to communicate. She had a thorough history of vital signs, with no signs of dehydration, jaundice, pallor, or edema. The patient's lower limbs were hypotonic and her upper limbs were normal. She experienced loss of sensation in her lower limbs, vibration, and proprioception. The patient's EMG-NCS report indicated sensory and motor axonal neuropathy (AMSAN variant). Plasmapheresis sessions were finished in our patient, and a very good result was achieved. In symptomatic GBS patients (related to large joints), physicians (and therapists) should consider rheumatoid arthritis when risk factors are present. Appropriate clinical treatment, which includes prompt evaluation of alternate diagnoses in the case of therapeutic failure, can improve patient outcomes.

Management of Spontaneous Chylothorax in a Neonate: A Medical Challenge.

Chylothorax or collection of lymphatic fluid in the pleural space is an exceedingly rare cause of pleural effusion and respiratory distress in neonates. In adults, prompt diagnosis and effective treatment regimen can aid in the resolution of chylothorax; however, in neonates treating the condition can be an onerous challenge for the pediatricians due to the rarity and perplexing clinical presentation. We elucidate a case of spontaneous chylothorax in a 15-day-old neonate who presented to us with respiratory distress, chest indrawing, and cyanosis for nine days. The prenatal and birth history of the patient were insignificant. The detailed laboratory and radiological assessment of the patient divulged a diagnosis of spontaneous chylothorax for which the patient was intubated. Unfortunately, the patient deteriorated and eventually expired on the 23rd postnatal day due to the complications of respiratory acidosis and hypoxemia.

The COVID-19 Infodemic: A Quantitative Analysis Through Facebook.

Background Social media is a crucial part of our daily life. Facebook, being the biggest social media platform, plays a significant role in the spread of information influencing the global response to the COVID-19 pandemic. Health care agencies like the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) use social media as a platform to impart information regarding COVID-19; simultaneously, there is a spread of misinformation on social media, masking the credible sources of information. Our research aims to assess the utility of Facebook in providing misinformation and testing its "fact-check policy." Methods An online search was conducted on Facebook by a newly created account to eliminate bias. The Facebook search bar was used to investigate multiple keywords. Data were tabulated in Microsoft Excel (Microsoft Corporation, Redmond, WA). Descriptive statistical analysis of Facebook accounts and posts was done using the Statistical Package for the Social Sciences (SPSS) version 26 (IBM Corp., Armonk, NY) while statistical importance was set a priority at a p-value of 0.05. Results Our study consisted of 454 Facebook posts. Most (22.5%) were posted by verified accounts and 23.9% by informal individual/group accounts. The tone for most (40.4%) COVID-19 information was serious while the most common (43.9%) topic was medical/public health. In total, 22.3% included misinformation, 19.6% were unverifiable, and 27.5% included correct information verifiable by the WHO or CDC. Conclusions Misinformation/unverifiable information related to the COVID-19 crisis is spreading at a distressing rate on social media. We quantified the misinformation and tested Facebook's "fact-check policy." We advise strict initiatives to control this infodemic and advise future researches to evaluate the accuracy of content being circulated on other social media platforms.