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1.
Sensors (Basel) ; 24(13)2024 Jun 30.
Artigo em Inglês | MEDLINE | ID: mdl-39001033

RESUMO

Presently, the prevailing approaches to assessing hinge joint damage predominantly rely on predefined damage indicators or updating finite element models (FEMs). However, these methods possess certain limitations. The damage indicator method requires high-quality monitoring data and demonstrates variable sensitivities of distinct indicators to damage. On the other hand, the FEM approach mandates a convoluted FEM update procedure. Hinge joint damage represents a major kind of defect in prefabricated assembled multi-girder bridges (AMGBs). Therefore, effective damage detection methods are imperative to identify the damage state of hinge joints. To this end, a stiffness-based method for the performance evaluation of hinge joints of AMGBs is proposed in this paper. The proposed method estimates hinge joint stiffness by solving the characteristic equations of the multi-beam system. In addition, this study introduces a method for determining baseline joint stiffness using design data and FEM. Subsequently, a comprehensive evaluation framework for hinge joints is formulated, coupling a finite element model with the baseline stiffness, thereby introducing a damage indicator rooted in stiffness ratios. To verify the effectiveness of the proposed method, strain and displacement correlations are analyzed using actual bridge monitoring data, and articulation joint stiffness is identified. The results underscore the capability of the proposed method to accurately pinpoint the location and extent of hinge joint damage.

2.
Bioorg Med Chem Lett ; 30(8): 127073, 2020 04 15.
Artigo em Inglês | MEDLINE | ID: mdl-32139326

RESUMO

A new water-soluble 4-amino-1, 8-naphthalimide based fluorescent sensor, with iminoacetic acid and iminoethoxyacetic acid as receptor contained two different arms, was developed. Under physiological pH conditions, it demonstrates good water solubility, high selectivity and sensitivity for sensing Zn2+ with about 20-fold enhancement in aqueous solution, with a characteristic emission band of 4-amino-1, 8-naphthalimide with a green color centered at 550 nm. It was applied successfully to detect Zn2+ in living cells.


Assuntos
Descoberta de Drogas , Corantes Fluorescentes/química , Zinco/análise , Teoria da Densidade Funcional , Relação Dose-Resposta a Droga , Corantes Fluorescentes/síntese química , Células HeLa , Humanos , Estrutura Molecular , Imagem Óptica , Solubilidade , Espectrometria de Fluorescência , Relação Estrutura-Atividade , Água/química
3.
Sci Rep ; 14(1): 8154, 2024 Apr 08.
Artigo em Inglês | MEDLINE | ID: mdl-38589524

RESUMO

To study the aerodynamic performance and wind-induced response of carbon fiber-reinforced polymer (CFRP) cables, CFRP cable was designed by replacing a steel cable in a tied arch bridge based on stiffness, strength and area equivalent criteria, respectively. The aerodynamic performance and wind-induced response of CFRP cable and steel cable were studied and compared by computational fluid dynamics (CFD) model. Based on the computational results, optimal cable replacement criterion was proposed for CFRP cable to replace steel cable. In addition, surface modification was conducted by engrooving vertical symmetric (VS), vertical asymmetric (VA) and helical symmetric (HS) V-shaped grooves to improve the aerodynamic performance and wind-induced response of CFRP cable. Results showed that CFRP cables exhibited inferior aerodynamic performance and wind-induced response in most cases. However, CFRP cable based on stiffness equivalent criterion exhibited better aerodynamic performance and wind-induced vibration properties compared to the other two cable replacement criteria, thus is regarded as the optimal substitute for steel cable. In addition, HS grooves generated symmetric disturbances and caused approximately equivalent boundary layer separation delays uniformly and continuously along the cable length, thus exhibiting better effect in decreasing the reverse flow region, the maximum negative flow velocity, the vortex shedding frequency and the wind-induced vibration amplitude of CFRP cable. Hence, the stiffness equivalent criterion combined with surface modification with HS V-shaped grooves was proposed to replace steel cable with CFRP cable. This study can provide insights into the aerodynamic performance and wind-induced response of CFRP cable and instructions for cable replacement practice.

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