Detalhe da pesquisa
1.
PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity.
Blood
; 139(4): 523-537, 2022 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35084470
2.
Targeting cancer metabolism through synthetic lethality-based combinatorial treatment strategies.
Curr Opin Oncol
; 30(5): 338-344, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29994904
3.
ß adrenergic signaling regulates hematopoietic stem and progenitor cell commitment and therapy sensitivity in multiple myeloma.
Haematologica
; 107(9): 2226-2231, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35511673
4.
In Silico Modeling-based Identification of Glucose Transporter 4 (GLUT4)-selective Inhibitors for Cancer Therapy.
J Biol Chem
; 290(23): 14441-53, 2015 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25847249
5.
Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy.
Blood
; 119(20): 4686-97, 2012 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22452979
6.
Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion.
iScience
; 27(4): 109591, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38632988
7.
Engineering Improved CAR T Cell Products with A Multi-Cytokine Particle Platform for Hematologic and Solid Tumors.
Adv Healthc Mater
; 13(14): e2302425, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38245855
8.
Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.
bioRxiv
; 2024 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38463958
9.
Cancer metabolism as a therapeutic target.
Oncology (Williston Park)
; 27(5): 460-7, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25184270
10.
The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma.
Blood Adv
; 7(14): 3485-3500, 2023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36920785
11.
Glucose transporters in cancer metabolism.
Curr Opin Oncol
; 24(6): 650-4, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22913968
12.
8-Aminoadenosine inhibits Akt/mTOR and Erk signaling in mantle cell lymphoma.
Blood
; 116(25): 5622-30, 2010 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20844237
13.
Mitochondrial metabolic determinants of multiple myeloma growth, survival, and therapy efficacy.
Front Oncol
; 12: 1000106, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36185202
14.
Therapeutic implications of mitochondrial stress-induced proteasome inhibitor resistance in multiple myeloma.
Sci Adv
; 8(39): eabq5575, 2022 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36170375
15.
Strategies to Overcome Failures in T-Cell Immunotherapies by Targeting PI3K-δ and -γ.
Front Immunol
; 12: 718621, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34512641
16.
Metformin reduces PD-L1 on tumor cells and enhances the anti-tumor immune response generated by vaccine immunotherapy.
J Immunother Cancer
; 9(11)2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34815353
17.
Expression of tdTomato and luciferase in a murine lung cancer alters the growth and immune microenvironment of the tumor.
PLoS One
; 16(8): e0254125, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34411144
18.
Targeting glucose consumption and autophagy in myeloma with the novel nucleoside analogue 8-aminoadenosine.
J Biol Chem
; 284(39): 26816-30, 2009 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19648108
19.
Downregulation of PA28α induces proteasome remodeling and results in resistance to proteasome inhibitors in multiple myeloma.
Blood Cancer J
; 10(12): 125, 2020 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33318477
20.
Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma.
Nat Commun
; 11(1): 1228, 2020 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144272