Detalhe da pesquisa
1.
Widespread macromolecular interaction perturbations in human genetic disorders.
Cell
; 161(3): 647-660, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25910212
2.
A proteome-scale map of the human interactome network.
Cell
; 159(5): 1212-1226, 2014 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25416956
3.
Cellular Heterogeneity of Activated Primary Human Macrophages and Associated Drug-Gene Networks: From Biology to Precision Therapeutics.
Circulation
; 148(19): 1459-1478, 2023 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37850387
4.
Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Promotes Macrophage Activation via LDL Receptor-Independent Mechanisms.
Circ Res
; 131(11): 873-889, 2022 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36263780
5.
Systems Approach to Discovery of Therapeutic Targets for Vein Graft Disease: PPARα Pivotally Regulates Metabolism, Activation, and Heterogeneity of Macrophages and Lesion Development.
Circulation
; 143(25): 2454-2470, 2021 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33821665
6.
Protein interaction networks provide insight into fetal origins of chronic obstructive pulmonary disease.
Respir Res
; 23(1): 69, 2022 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35331221
7.
Exploring the cross-phenotype network region of disease modules reveals concordant and discordant pathways between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.
Hum Mol Genet
; 28(14): 2352-2364, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30997486
8.
Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.
Circulation
; 139(1): 78-96, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30586693
9.
Whole exome sequencing analysis in severe chronic obstructive pulmonary disease.
Hum Mol Genet
; 27(21): 3801-3812, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30060175
10.
Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.
Circulation
; 138(4): 377-393, 2018 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29588317
11.
Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets.
Proc Natl Acad Sci U S A
; 113(18): 4976-81, 2016 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27091990
12.
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.
Hum Mol Genet
; 24(11): 3005-20, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25586491
13.
Network-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits.
Mol Cell Proteomics
; 12(11): 3398-408, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23882023
14.
A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.
Lancet
; 376(9750): 1393-400, 2010 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20971364
15.
Gene prioritization in Type 2 Diabetes using domain interactions and network analysis.
BMC Genomics
; 11: 84, 2010 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20122255
16.
Middle ear adenoma with neuroendocrine differentiation: Report of a rare case.
Indian J Cancer
; 57(1): 98-101, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32129301
17.
Robustness and lethality in multilayer biological molecular networks.
Nat Commun
; 11(1): 6043, 2020 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33247151
18.
Discovering the genes mediating the interactions between chronic respiratory diseases in the human interactome.
Nat Commun
; 11(1): 811, 2020 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32041952
19.
Mechanical forces induce an asthma gene signature in healthy airway epithelial cells.
Sci Rep
; 10(1): 966, 2020 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31969610
20.
FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses.
Nat Commun
; 11(1): 6398, 2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33328473