Detalhe da pesquisa
1.
GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment.
Am J Physiol Endocrinol Metab
; 308(4): E283-93, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25491724
2.
General control nonderepressible 2 (GCN2) kinase protects oligodendrocytes and white matter during branched-chain amino acid deficiency in mice.
J Biol Chem
; 288(43): 31250-60, 2013 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24019515
3.
Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle.
Cell Metab
; 6(3): 181-94, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17767905
4.
Transamination is required for {alpha}-ketoisocaproate but not leucine to stimulate insulin secretion.
J Biol Chem
; 285(44): 33718-26, 2010 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20736162
5.
Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels.
J Biol Chem
; 285(15): 11348-56, 2010 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20093359
6.
Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's disease.
Am J Physiol Endocrinol Metab
; 301(1): E49-61, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21505144
7.
Leucine supplementation of drinking water does not alter susceptibility to diet-induced obesity in mice.
J Nutr
; 139(4): 715-9, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19244380
8.
Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver.
Diabetes
; 54(12): 3458-65, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16306362
9.
The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment.
Metabolism
; 55(10): 1411-9, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16979414
10.
Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db/db mice.
Diabetes
; 53(2): 410-7, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14747292
11.
Mechanisms by which liver-specific PEPCK knockout mice preserve euglycemia during starvation.
Diabetes
; 52(7): 1649-54, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12829628
12.
Antisense oligonucleotides targeted against glucocorticoid receptor reduce hepatic glucose production and ameliorate hyperglycemia in diabetic mice.
Metabolism
; 54(7): 848-55, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15988691
13.
Leucine and protein metabolism in obese Zucker rats.
PLoS One
; 8(3): e59443, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23527196
14.
Disruption of BCAA metabolism in mice impairs exercise metabolism and endurance.
J Appl Physiol (1985)
; 108(4): 941-9, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20133434
15.
Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells.
J Clin Invest
; 119(6): 1678-87, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19411760
16.
Non-invasive detection of fatty liver in dairy cows by digital analyses of hepatic ultrasonograms.
J Dairy Res
; 75(1): 84-9, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18226302
17.
Skeletal and cardiac myopathy in HIV-1 transgenic rats.
Am J Physiol Endocrinol Metab
; 295(4): E964-73, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18713959
18.
Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism.
Am J Physiol Endocrinol Metab
; 293(6): E1552-63, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17925455
19.
Gene-altered mice and metabolic flux control.
J Biol Chem
; 278(35): 32485-8, 2003 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-12788933