Assuntos
American Heart Association , Fibrilação Atrial/terapia , Cardiologia/normas , Guias de Prática Clínica como Assunto/normas , Sociedades Médicas/normas , Procedimentos Cirúrgicos Torácicos/normas , Comitês Consultivos/normas , Fibrilação Atrial/epidemiologia , Fibrilação Atrial/fisiopatologia , Gerenciamento Clínico , Frequência Cardíaca/fisiologia , Humanos , Relatório de Pesquisa/normas , Estados Unidos/epidemiologiaRESUMO
BACKGROUND: The implantable cardioverter defibrillator (ICD) reduces mortality in patients at risk for life-threatening arrhythmias via high energy shock. The Florida Shock Anxiety Scale (FSAS) was developed to measure ICD patient shock-related anxiety. Initial psychometric evaluation revealed good reliability and validity. The purpose of this study was to examine the psychometrics of the FSAS in a large US sample of ICD patients. METHODS: Participants were recruited via e-mail and the survey was completed online. Ultimately, 443 ICD patients (359 male and 421 White) completed the 10-item FSAS. RESULTS: Means for FSAS were comparable to previously published data (M = 15.18, SD = 6.5). Interitem reliability was good (Cronbach's α= 0.89). The FSAS was negatively correlated with single-item measures of emotional well-being (r =-0.378, P < 0.01), sense of security (r =-0.365, P < 0.01), perceived general health (r =-0.185, P < 0.01), and quality of life (r =-0.216, P < .01), demonstrating discriminant validity. Convergent validity was supported through significant correlations with number of shocks (r = 0.464, P < 0.01) and reported disruptiveness of shock (r = 0.484, P < 0.01). Confirmatory factor analysis revealed that a single (second-order) factor model (χ(2) [34] = 75.34, P < 0.05, comparative fit index = 0.98, root mean-square error of approximation = 0.05) had the best fit. CONCLUSIONS: Shock anxiety as a construct can be measured in a reliable and valid method by the FSAS. These nationally representative data suggest that a single score for shock anxiety is an easy to use and appropriate method of assessment.
Assuntos
Ansiedade/diagnóstico , Arritmias Cardíacas/diagnóstico , Arritmias Cardíacas/prevenção & controle , Psicometria/métodos , Índice de Gravidade de Doença , Inquéritos e Questionários , Adulto , Idoso , Idoso de 80 Anos ou mais , Ansiedade/epidemiologia , Arritmias Cardíacas/complicações , Arritmias Cardíacas/epidemiologia , Comorbidade , Desfibriladores Implantáveis , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Psicometria/estatística & dados numéricos , Reprodutibilidade dos Testes , Medição de Risco , Sensibilidade e Especificidade , Estados Unidos , Adulto JovemRESUMO
BACKGROUND: Atrial fibrillation (AF) can have a significant effect on quality of life (QoL). Other chronic diseases are known to not only affect the patient but to also impact the QoL of persons living with them. Scant data exist on the QoL effect of AF in spouses/significant others (SOs). METHODS: An anonymous survey regarding the perceived effect of AF on QoL was designed and distributed to both patients and spouses/SOs during an educational symposium about living with AF. Both were asked to fill out the survey independently according to how their life was affected by either their AF or their partner's AF. Questions included demographics, perceived impairment of overall QoL on a 5-point scale, as well as effect on subcategories of QoL, namely daily activity, work life, sex life, physical activity, psychological well-being, and social activity. RESULTS: Five hundred and sixty-eight subjects completed the survey of which 411 were AF patients and 129 were spouses/SOs. The perceived effect of AF on overall QoL (N = 527) was similar in patients and spouses (AF patients: mild 42.0%, moderate 26.0%, severe 32.0% vs. spouses: 44.1%, 25.2%, 31.7%; P = 0.917). This result did not change when adjusted for age and gender. There was also no significant difference between patients and spouses in the subcategories of QoL with the exception of the perceived effect on work life, which was greater in patients than spouses (P = 0.041). CONCLUSIONS: AF has a similar perceived impact on the QoL of spouses and patients. QoL improvement strategies for patients with AF should take spouses into account.
Assuntos
Fibrilação Atrial , Saúde da Família , Qualidade de Vida , Cônjuges , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeAssuntos
Adaptação Psicológica , Desfibriladores Implantáveis/psicologia , Transtornos de Estresse Pós-Traumáticos/psicologia , Estresse Psicológico/psicologia , Ferimentos e Lesões/psicologia , Humanos , Acontecimentos que Mudam a Vida , Qualidade de Vida , Fatores de Risco , Apoio Social , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Estresse Psicológico/epidemiologiaAssuntos
Insuficiência Cardíaca/terapia , Cooperação do Paciente , Educação de Pacientes como Assunto/normas , Comportamento de Redução do Risco , Doença Crônica , Gerenciamento Clínico , Insuficiência Cardíaca/diagnóstico , Insuficiência Cardíaca/psicologia , Humanos , Cooperação do Paciente/psicologia , Educação de Pacientes como Assunto/métodosRESUMO
The ability to remotely monitor important physiologic parameters will dramatically change how we care for patients. We are on the threshold of this era with currently available implantable cardiac devices. Current devices provide a plethora of important arrhythmia- and heart failure-related information. Dealing with this "flood" of information and a new "work flow" can be a challenge. Careful planning can reduce the stress and improve patient care. Electrophysiologists and heart failure practitioners are on the cutting edge of this revolution in health care and therefore are required to deal with the challenges this technology brings. However, they also have the opportunity to shape the future of heart failure management.
Assuntos
Fibrilação Atrial/fisiopatologia , Eletrocardiografia/instrumentação , Insuficiência Cardíaca/fisiopatologia , Monitorização Ambulatorial/instrumentação , Desfibriladores Implantáveis , Eletrocardiografia Ambulatorial , Humanos , Marca-Passo Artificial , Telemetria/instrumentaçãoRESUMO
BACKGROUND: Common psychological adjustment difficulties have been identified for groups of implantable cardioverter defibrillator patients, such as those who are young (<50 years old), have been shocked, and are female. Specific aspects and concerns, such as fears of death or shock and body image concerns, that increase the chance of distress, have not been examined in different aged female implantable cardioverter defibrillator (ICD) recipients. The aim of the study was to investigate these areas of adjustment across three age groups of women from multiple centers. METHODS: Eighty-eight female ICD patients were recruited at three medical centers: Shands Hospital at the University of Florida, Brigham and Women's Hospital in Boston, and Royal North Shore Hospital in Sydney, Australia. Women completed individual psychological assessment batteries, measuring the constructs of shock anxiety, death anxiety, and body image concerns. Medical record review was conducted for all patients regarding cardiac illnesses and ICD-specific data. RESULTS: Multivariate and univariate analyses of variance revealed that younger women reported significantly higher rates of shock and death anxiety (Pillai's F=3.053, P=0.018, eta2p=0.067) and significantly greater body image concerns (Pillai's F=4.198, P=0.018, eta2p=0.090) than middle- and older-aged women. CONCLUSIONS: Women under the age of 50 appear to be at greater risk for the development of psychosocial distress associated with shock anxiety, death anxiety, and body image. Clinical-based strategies and interventions targeting these types of adjustment difficulties in younger women may allow for improved psychosocial and quality of life outcomes.
Assuntos
Ansiedade/epidemiologia , Ansiedade/psicologia , Atitude Frente a Morte , Desfibriladores Implantáveis/psicologia , Desfibriladores Implantáveis/estatística & dados numéricos , Traumatismos por Eletricidade/psicologia , Medição de Risco/métodos , Adulto , Distribuição por Idade , Idoso , Austrália/epidemiologia , Boston/epidemiologia , Traumatismos por Eletricidade/epidemiologia , Feminino , Florida/epidemiologia , Humanos , Internacionalidade , Pessoa de Meia-Idade , Fatores de Risco , Saúde da MulherRESUMO
BACKGROUND: Patients with cystic fibrosis have altered levels of plasma fatty acids. We previously demonstrated that arachidonic acid levels are increased and docosahexaenoic acid levels are decreased in affected tissues from cystic fibrosis-knockout mice. In this study we determined whether humans with mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene have a similar fatty acid defect in tissues expressing CFTR. METHODS: Fatty acids from nasal- and rectal-biopsy specimens, nasal epithelial scrapings, and plasma were analyzed from 38 subjects with cystic fibrosis and compared with results in 13 obligate heterozygotes, 24 healthy controls, 11 subjects with inflammatory bowel disease, 9 subjects with upper respiratory tract infection, and 16 subjects with asthma. RESULTS: The ratio of arachidonic to docosahexaenoic acid was increased in mucosal and submucosal nasal-biopsy specimens (P<0.001) and rectal-biopsy specimens (P=0.009) from subjects with cystic fibrosis and pancreatic sufficiency and subjects with cystic fibrosis and pancreatic insufficiency, as compared with values in healthy control subjects. In nasal tissue, this change reflected an increase in arachidonic acid levels and a decrease in docosahexaenoic acid levels. In cells from nasal mucosa, the ratio of arachidonic to docosahexaenoic acid was increased in subjects with cystic fibrosis (P<0.001), as compared with healthy controls, with values in obligate heterozygotes intermediate between these two groups (P<0.001). The ratio was not increased in subjects with inflammatory bowel disease. Subjects with asthma and those with upper respiratory tract infection had values intermediate between those in subjects with cystic fibrosis and those in healthy control subjects. CONCLUSIONS: These data indicate that alterations in fatty acids similar to those in cystic fibrosis-knockout mice are present in CFTR-expressing tissue from subjects with cystic fibrosis.
Assuntos
Ácido Araquidônico/metabolismo , Fibrose Cística/metabolismo , Ácidos Docosa-Hexaenoicos/metabolismo , Asma/metabolismo , Biópsia , Estudos de Casos e Controles , Regulador de Condutância Transmembrana em Fibrose Cística/genética , Regulador de Condutância Transmembrana em Fibrose Cística/metabolismo , Ácidos Graxos/sangue , Ácidos Graxos/metabolismo , Heterozigoto , Humanos , Doenças Inflamatórias Intestinais/metabolismo , Mutação , Mucosa Nasal/metabolismo , Reto/metabolismo , Valores de Referência , Infecções Respiratórias/metabolismoAssuntos
Adaptação Psicológica , Cuidadores/psicologia , Desfibriladores Implantáveis , Cardiopatias/terapia , Parceiros Sexuais/psicologia , Ansiedade/etiologia , Aprendizagem da Esquiva , Coito , Desfibriladores Implantáveis/efeitos adversos , Depressão/etiologia , Família/psicologia , Cardiopatias/psicologia , Humanos , Relações Interpessoais , Aceitação pelo Paciente de Cuidados de Saúde , Papel (figurativo) , Estresse Psicológico/etiologia , Estresse Psicológico/terapiaRESUMO
This article illustrates the important role that lead extraction plays in the management of patients with cardiac implantable electronic devices. Individualized care of the patient is paramount when considering lead management strategies. The critical care nurse must have a comprehensive understanding of the indications, procedural considerations, and preprocedural and postprocedural care for patients undergoing lead extraction procedures, thereby improving patient safety and maximizing patient outcomes.
Assuntos
Enfermagem de Cuidados Críticos , Desfibriladores Implantáveis/efeitos adversos , Remoção de Dispositivo/enfermagem , Cardiopatias/terapia , Monitorização Fisiológica/efeitos adversos , Monitorização Fisiológica/instrumentação , Marca-Passo Artificial/efeitos adversos , Cardiopatias/enfermagem , Cardiopatias/fisiopatologia , Humanos , Monitorização Fisiológica/enfermagem , Segurança do PacienteRESUMO
OBJECTIVE: We hypothesized that a new minimal ventricular pacing mode (MVP) that provides AAI/R pacing with ventricular monitoring and back-up DDD/R pacing as needed during AV block (AVB) would significantly reduce cumulative percent ventricular pacing compared to DDD/R. BACKGROUND: Conventional DDD/R mode often results in high cumulative percent ventricular pacing that may adversely affect ventricular function and increase risk of heart failure and atrial fibrillation. METHODS: MVP was made operational in 30 patients with DDD/R implantable cardioverter-defibrillators (ICDs) and no history of AVB. Patients were randomized to one week each in DDD/R and MVP. Holter monitor recordings (ECG, intracardiac electrograms, and event markers) and device diagnostics were analyzed for cumulative % atrial paced (Cum%AP), cumulative percent ventricular pacing, and frequency and duration of DDD/R pacing back-up. Diaries were used to report symptoms. RESULTS: Age of the study population was 61 years +/- 12 years and 83% were male. Baseline PR interval was 204 ms +/- 32 ms and programmed AV intervals (DDD/R) were 200 ms +/- 50 ms (paced)/167 ms +/- 54 ms (sensed). Cum%AP was similar between MVP and DDD/R (47.9 +/- 37 vs 46.3 +/- 36). Cumulative percent ventricular pacing was significantly lower in MVP vs DDD/R (3.79 +/- 16.3 vs 80.6 +/- 33.8, P < .0001). Back-up DDD/R pacing during MVP operation due to transient AVB occurred in 10% of patients (9.3 +/- 7.4 [range 1-15] episodes/patient-day, duration 39.7 minutes +/- 156 minutes). Fifteen percent of AV intervals during MVP operation exceeded 300 ms. No significant symptoms were reported during MVP operation. CONCLUSIONS: MVP dramatically reduced cumulative percent ventricular pacing compared to DDD/R while maintaining AV synchrony and providing sensor-modulated atrial pacing support. Intermittent oscillations between MVP and DDD/R during transient AV block appeared safe and well tolerated.
Assuntos
Nó Atrioventricular/fisiopatologia , Estimulação Cardíaca Artificial/métodos , Desfibriladores Implantáveis , Bloqueio Cardíaco/terapia , Estudos Cross-Over , Cardioversão Elétrica , Eletrocardiografia Ambulatorial , Feminino , Bloqueio Cardíaco/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Projetos Piloto , Estudos Prospectivos , Método Simples-Cego , Resultado do TratamentoRESUMO
The aim of this study was to survey cystic fibrosis (CF) patients to determine the frequency of breast-feeding and its association with onset and severity of CF symptoms. Three thousand, two hundred questionnaires were sent to 30 accredited CF centers for anonymous completion. Eight hundred and sixty-three questionnaires were returned and scanned into a database. All results were adjusted for age at time of filling out the questionnaire. Age at onset of symptoms, percent forced expired volume in 1 sec (FEV1%) predicted, and intravenous (IV) antibiotic use were analyzed based on breast-feeding history. Approximately 49% of respondents received human breast milk at some time, but only 18% were exclusively breast-fed. Breast-feeding exclusively for greater than 6 months was associated with a decrease in disease severity based on recent intravenous antibiotic use compared to no breast-feeding (P = 0.03). There was no statistically significant change in onset of symptoms in the setting of breast-feeding; however, a trend toward delayed onset was seen in those receiving human milk. Fifty-three percent of those who breast-fed exclusively > or = 6 months had FEV1% values > 90%, compared to 47% of those not breast-fed. This is a suggestive but not statistically significant difference. In conclusion, breast-feeding for > or = 6 months is associated with decreased use of intravenous antibiotics in the 2 years prior to administering the questionnaire. This survey indicates that breast-feeding is not harmful to children with CF, and may be beneficial.
Assuntos
Aleitamento Materno/estatística & dados numéricos , Fibrose Cística/fisiopatologia , Adolescente , Adulto , Antibacterianos/uso terapêutico , Criança , Pré-Escolar , Fibrose Cística/tratamento farmacológico , Uso de Medicamentos/estatística & dados numéricos , Volume Expiratório Forçado/fisiologia , Humanos , Lactente , Fórmulas Infantis , Avaliação de Resultados em Cuidados de Saúde , Índice de Gravidade de Doença , Inquéritos e Questionários , Fatores de TempoRESUMO
BACKGROUND: Implantable cardioverter defibrillator (ICD) shocks terminate potentially life-threatening arrhythmias and may alter patient behavior. Patients are aware of which activities they have the ability to perform, but they may choose to avoid these behaviors after receiving a shock. This study examined ICD patient ability and avoidance of progressively exertive behaviors. METHODS: ICD patients (N = 443) across the United States were surveyed using an online measure including the 12-item Duke Activity Status Index. RESULTS: As expected, many patients reported being unable to participate in more physically exertive activities such as strenuous athletic exertion (68.8%), sex (35.4%), and running a short distance (49.0%). Avoidance rates were also relatively high, as patients who reported being able to participate in these activities also reported avoiding them (ie, strenuous athletics, 76.1%). Similarly, the majority of patients reported ability to engage in sexual activity (64.6%) but many chose to avoid sexual activity (51.0%). Multiple reasons were reported for avoidance, including fear of shock, fear of heart rate increase, doctor instruction, no desire, and an "other" option. CONCLUSION: Many ICD patients experience behavioral limitations because of both a perceived inability and preference to avoid exertive activities, and possibly a prescription to do so, particularly strenuous athletic exertion. Clinical and research attention to ICD patient activity levels and reasons for avoidance may improve daily functioning and help patients return to preimplant levels of activity.